img
img
The Marmara earthquake: admission laboratory features of patients with nephrological problems   
Yazarlar (12)
Mehmet Şükrü Sever
İstanbul Üniversitesi, Türkiye
Ekrem Erek
Türkiye
Raymond Vanholder
Türkiye
İshak Çetin Özener
Marmara Üniversitesi, Türkiye
M Yavuz
Türkiye
H Ergin
Türkiye
H Kiper
Türkiye
Didem Korular
Türkiye
Prof. Dr. Başol CANBAKAN Prof. Dr. Başol CANBAKAN
Kafkas Üniversitesi, Türkiye
Selim Turgay Arınsoy
Gazi Üniversitesi, Türkiye
Wa Vanbiesen
Türkiye
Ne Lameire
Türkiye
Devamını Göster
Özet

Background

Earthquakes are major causes of morbidity and mortality. North-western Turkey was struck by a devastating earthquake in August 1999, which caused several thousand deaths. Among the most important morbid events in survivors were acute nephrological problems.

Methods

Within the first week of the disaster, specific questionnaires asking about 63 clinical and laboratory parameters were sent to 35 reference hospitals that were treating the victims. Of the registered 639 victims, 423 were admitted within the first 3 days of the disaster; the admission laboratory data of these 423 patients are the subject of this analysis.

Results

In the 423 patients (233 males, mean age 31.3+/-14.4 years), time under the rubble was 10.7+/-10.4 h. Mean values at admission were as follows: serum potassium 5.4+/-1.3 mEq/l, creatine phosphokinase 58205+/-77889 IU/l, albumin 2.6+/-0.7 g/dl, phosphorus 5.2+/-1.8 mg/dl, haematocrit 35.0+/-9.3%, leukocyte count 14945+/-6614/mm(3), platelet count 183975+/-134012/mm(3), blood urea nitrogen 55.1+/-28.9 mg/dl, and creatinine 3.9+/-2.3 mg/dl. Serum potassium above 6.5 mEq/l was noted in 91 patients (22.7%), an alarming finding for risk of fatal arrhythmias. Non-survivors were characterized by higher figures of serum potassium (P=0.001), as well as lower haematocrit (P=0.028), platelets (P<0.001), and serum albumin (P=0.003). In a multivariate analysis model of admission laboratory parameters, serum creatinine (P<0.001, o.r.=2.19), potassium (P=0.001, o.r.=3.64), and phosphorus (P=0.004, o.r.=1.78) predicted dialysis needs, whereas serum albumin (P=0.028, o.r.=0.23) and creatinine (P=0.039, o.r.=0.60) were related to mortality.

Conclusions

Admission laboratory data may be useful for predicting dialysis needs and survival chance of disaster victims. High incidences of some life-threatening abnormalities dictate the need for empirical therapy even in the field.
Anahtar Kelimeler
Makale Türü Özgün Makale
Makale Alt Türü SSCI, AHCI, SCI, SCI-Exp dergilerinde yayınlanan tam makale
Dergi Adı NEPHROLOGY DIALYSIS TRANSPLANTATION
Dergi ISSN 0931-0509 Wos Dergi Scopus Dergi
Dergi Tarandığı Indeksler SCI-Expanded
Makale Dili İngilizce
Basım Tarihi 01-2002
Cilt No 17
Sayı 6
Sayfalar 1025 / 1031
BM Sürdürülebilir Kalkınma Amaçları
Atıf Sayıları

Paylaş