Yazarlar (7) |
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![]() Kafkas Üniversitesi, Türkiye |
![]() Sağlık Bilimleri Üniversitesi, Türkiye |
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Özet |
PurposeWe aimed to investigate the association between atherosclerotic changes in the common carotid artery (CA) and conjunctival and corneal calcification (CCC) in maintenance hemodialysis (MHD) patients.MethodsFifty eyes of MHD patients with the highest CCC scores were enrolled. CCCs were scored according to the method described by Tokuyama et al. The eyes with the highest CCC scores were selected for further analysis. According to their CCC scores, the patients were classified into 3 groups: mild (0-2 score), moderate (3-5), and severe (6-10 score). Atherosclerosis of the common CA was evaluated by determination of intima-media thickness (IMT), peak systolic (PSV) and end diastolic (EDV) flow velocities, pulsatility index, and resistive index values by using Doppler ultrasonography.ResultsThe mean IMT of the CA was 0.61 ± 0.09 mm in the mild group, 0.82 ± 0.16 mm in the moderate group, and 1.21 ± 0.32 mm in the severe group (P < 0.001). The PSV and EDV were significantly higher in the severe group than in the mild and moderate groups (all, P < 0.001). The CCC score was positively correlated with the duration of hemodialysis, ocular surface disease index score, IMT, PSV, EDV, lymphocyte, calcium, and sedimentation rate. In multiple stepwise linear regression analysis, IMT was the best predictive factor for the CCC score (R = 0.812, β = 9.526 ± 1.05, and P < 0.001).ConclusionsOur results suggest that chronic ocular ischemia due to atherosclerotic changes may have a role in the formation or progression of CCC in MHD patients. |
Anahtar Kelimeler |
Makale Türü | Özgün Makale |
Makale Alt Türü | SSCI, AHCI, SCI, SCI-Exp dergilerinde yayınlanan tam makale |
Dergi Adı | Cornea |
Dergi ISSN | 0277-3740 Wos Dergi Scopus Dergi |
Dergi Tarandığı Indeksler | SCI |
Makale Dili | İngilizce |
Basım Tarihi | 01-2017 |
Cilt No | 36 |
Sayı | 1 |
Sayfalar | 68 / 73 |
Doi Numarası | 10.1097/ICO.0000000000001034 |
Makale Linki | http://content.wkhealth.com/linkback/openurl?sid=WKPTLP:landingpagean=00003226-201701000-00015 |