| Yazarlar |
Dr. Öğr. Üyesi Şükran YEDİEL ARAS
Türkiye |
Doç. Dr. Pınar AKSU KILIÇLE
Türkiye |
Prof. Dr. Sevda ELİŞ YILDIZ
Kafkas Üniversitesi, Türkiye |
Erhan Uluman
Türkiye |
|
Buket Bakır
Türkiye |
Prof. Dr. Ebru KARADAĞ SARI
Türkiye |
Prof. Dr. Serpil DAĞ
Türkiye |
| Özet |
| Objective: This study aimed to investigate the effects of Chia (Salvia hispanica L.) oil and Dandelion (Taraxacum Officinale) extract on Tumor Necrosis Factor-α (TNF-α) and Interleukin 6 (IL-6) release in liver tissue of diabetic rats. Material and Method: Experimental groups were created as control, sham, chia, dandelion, diabetes (DM), diabetes+chia (DC), and diabetes +dandelion (DD). Body weight and blood glucose measurements were taken on the 1st, 3rd, and 17th days of the study and evaluated statistically. A one-way ANOVA test was performed to determine the differences between the groups. The Duncan test was used to compare significant differences between groups. At the end of the study, Masson's trichrome staining and Hematoxylin-Eosin staining were employed for histological examinations of liver tissues, and the distribution of TNF-α and IL-6 was examined by applying the Streptavidin-biotin peroxidase method. Results: It was determined that body weight and blood glucose measurements were significantly decrease for the DC group compared to other groups. Immunoreactivity of TNF-α and IL-6 was found to decrease in DC and DD groups at close to the control levels. Conclusion: Based on our results, it was thought that the use of chia and dandelion in diabetes may contribute to the alleviation of disease-related complications by having a positive effect on proinflammatory cytokine levels. |
| Anahtar Kelimeler |
| Chia,Dandelion,Diabetes mellitus,IL-6,TNF-α |
| Makale Türü | Özgün Makale |
| Makale Alt Türü | Ulusal alan endekslerinde (TR Dizin, ULAKBİM) yayımlanan tam makale |
| Dergi Adı | Turkish Journal of Veterinary Research |
| Dergi ISSN | 2602-3695 |
| Dergi Tarandığı Indeksler | TR DİZİN |
| Makale Dili | İngilizce |
| Basım Tarihi | 07-2022 |
| Cilt No | 6 |
| Sayı | 2 |
| Sayfalar | 43 / 52 |
| Doi Numarası | 10.47748/tjvr.1062162 |
| Makale Linki | https://dergipark.org.tr/en/pub/tjvr/issue/73416/1062162 |
| Atıf Sayıları |
