| Yazarlar |
Gökhan Nur
Gaziantep Üniversitesi, Türkiye |
|
Mümtaz Nazlı
Muğla Sıtkı Koçman Üniversitesi, Türkiye |
Sevda ELİŞ YILDIZ
Kafkas Üniversitesi, Türkiye |
| Özet |
| The objective of this study was to investigate the effects of capsaicin on the testis distribution of transforming growth factorbeta 2 (TGFβ2) and gene expression using real-time PCR in pubescent rats. In this study, rats were divided into 3 groups: capsaicin(CAP), sham, and control. Te CAP group was injected with 1 mg/kg doses of capsaicin (10% ethanol and 1% Tween in an 80% distilledwater mixture) subcutaneously every day for a period of 1 week. The sham group was injected with a solution of 10% ethanol and 1%Tween in a mixture of 80% distilled water and nothing was injected in control rats. Regarding the histological appearance of testicularsections, the sham and control groups maintained the structure of connective tissue and seminiferous tubule, while in the CAP group,gaps among the tubule cells, invagination in the tubule cell wall, tubular integrity degradation, and breakdowns in the connectivetissue were also observed. TGFβ2 immunoreactivity was observed in mature spermatids of all groups; moreover, immunoreactivitiesin the groups were similar in intensity. Tese results demonstrate that capsaicin, which is already known to afect gastrointestinal,cardiovascular, and respiratory systems, also interferes with the expression of TGFβ2 in rat testis. |
| Anahtar Kelimeler |
| Makale Türü | Özgün Makale |
| Makale Alt Türü | SSCI, AHCI, SCI, SCI-Exp dergilerinde yayımlanan tam makale |
| Dergi Adı | TURKISH JOURNAL OF VETERINARY AND ANIMAL SCIENCES |
| Dergi ISSN | 1300-0128 |
| Dergi Tarandığı Indeksler | SCI-Expanded |
| Makale Dili | İngilizce |
| Basım Tarihi | 07-2014 |
| Cilt No | 38 |
| Sayı | 4 |
| Sayfalar | 377 / 382 |
| Doi Numarası | 10.3906/vet-1302-16 |
| Makale Linki | http://online.journals.tubitak.gov.tr/openDoiPdf.htm?mKodu=vet-1302-16 |
| Atıf Sayıları | |
| TRDizin | 2 |
