| Yazarlar |
Dr. Öğr. Üyesi Şükran YEDİEL ARAS
Kafkas Üniversitesi, Türkiye |
Prof. Dr. Ebru KARADAĞ SARI
Kafkas Üniversitesi, Türkiye |
Prof. Dr. Serpil DAĞ
Kafkas Üniversitesi, Türkiye |
| Özet |
| Objective: This study was conducted with the purpose of investigating the distribution of the ActivatingTranscription Factor 6 (ATF6) and the Nerve Growth Factor (NGF) in the duodenum tissue of diabetic andnon-diabetic rats.Material and Method: Eighteen female Sprague dawley rats were randomly divided into three groups as thecontrol, sham and diabetes groups. Routine histological and immunohistochemical methods were appliedon the duodenum tissues collected at the end of the study.Results: It was determined that the villus length measurements showed a statistically significant differencebetween the control and diabetes groups. There was NGF immunoreactivity which was moderate anddiffuse cytoplasmic in the villus intestinalis and muscularis layer in all groups, weak in the crypts andglands in the control and sham groups and moderate and diffuse cytoplasmic in the diabetes group. ATF6immunoreactivity was determined moderate in the villus intestinalis, crypts, glands and muscularis layerin the control and sham groups and strong diffuse cytoplasmic in the diabetes group. Conclusion: It wasdetermined that both NGF and ATF6 immunoreactivity increased in the duodenum tissue of the rats onwhich diabetes was induced experimentally. |
| Anahtar Kelimeler |
| dibetes,duodenum,NGF,ATF6 |
| Makale Türü | Özgün Makale |
| Makale Alt Türü | Uluslararası alan indekslerindeki dergilerde yayımlanan tam makale |
| Dergi Adı | Turkish Journal of Veterinary Research |
| Dergi ISSN | 2602-3695 |
| Dergi Tarandığı Indeksler | CABI Abstract, TRDizin, EBSCO, Index Copernicus, Embase, Crossref |
| Makale Dili | İngilizce |
| Basım Tarihi | 03-2021 |
| Cilt No | 5 |
| Sayı | 1 |
| Sayfalar | 41 / 49 |
| Doi Numarası | 10.47748/tjvr.867947 |
| Atıf Sayıları |
