Yazarlar |
Gökhan Perincek
Türkiye |
Canver Önal
Türkiye |
Timor OMAR
Kafkas Üniversitesi, Türkiye |
Özet |
Background: The diagnostic value for chest CT has been widely established in patients with COVID-19. However, there is a lack of satisfactory data about the prognostic value of chest CTs. This study investigated the prognostic value of chest CTs in COVID-19 patients. Materials and Methods: A total of 521 symptomatic patients hospitalized with COVID-19 were included retrospectively. Clinical, laboratory, and chest CT characteristics were compared between survivors and non-survivors. Concerning chest CT, for each subject, a semi-quantitative CT severity scoring system was applied. Results: Most patients showed typical CT features based on the likelihood of COVID-19. The global CT score was significantly higher in non-survivors (median (IQR), 1 (0−6) vs. 10 (5−13), p < 0.001). A cut-off value of 5.5 for the global CT score predicted in-hospital mortality with 74% sensitivity and 73% specificity. Global CT score, age, C-reactive protein, and diabetes were independent predictors of in-hospital mortality. The global CT score was significantly correlated with the C-reactive protein, D-dimer, pro-brain natriuretic peptide, and procalcitonin levels. Conclusion: The global CT score could provide valuable prognostic data in symptomatic patients with COVID-19. |
Anahtar Kelimeler |
COVID-19 | mortality | computed tomography | chest CT | prognosis |
Makale Türü | Özgün Makale |
Makale Alt Türü | SSCI, AHCI, SCI, SCI-Exp dergilerinde yayımlanan tam makale |
Dergi Adı | ADVANCES IN RESPIRATORY MEDICINE |
Dergi ISSN | 2451-4934 |
Dergi Tarandığı Indeksler | Imergin Sources Citation Index (Web of Science) |
Makale Dili | İngilizce |
Basım Tarihi | 08-2022 |
Cilt No | 90 |
Sayı | 4 |
Sayfalar | 312 / 322 |
Doi Numarası | 10.3390/arm90040041 |
Makale Linki | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9717320/ |