| Yazarlar |
Dr. Öğr. Üyesi Ümit YILDIRIM
Kafkas Üniversitesi, Türkiye |
Dr. Öğr. Üyesi Mehmet EZER
Kafkas Üniversitesi, Türkiye |
Dr. Öğr. Üyesi Mehmet USLU
Kafkas Üniversitesi, Türkiye |
Rasim Güzel
Türkiye |
|
Kemal Sarıca
Biruni Üniversitesi, Türkiye |
| Özet |
| The purpose of this article is to identify the factors that predict the success of retrograde intrarenal surgery (RIRS), with a focus on the effect of renal parenchymal thickness and anticoagulant use on stone-free rates. From February 2014 to April 2022, cases of kidney stones treated with RIRS at our clinic were retrospectively screened. The study included 642 cases meeting all inclusion and exclusion criteria. The patients who were observed to be stone free after a single session of RIRS were assigned to Group F, while those with residual fragments were assigned to Group R. Group F comprised 472 patients, while Group R included 170 patients. The two groups have compared certain preoperative and postoperative laboratory and radiological parameters. The infundibulopelvic angle was significantly more acute in Group R (45.63 ± 16.25 vs. 49.28 ± 15.36, p = 0.011) while patients in Group F tended to have thicker parenchyma (27.39 ± 8.38 vs. 22.88 ± 5.56, p < 0.001). In our analysis of multivariate logistic regression, stone size (OR: 1.074, 1.037-1.113; p < 0.001), lower calyceal location (OR: 0.550, 95% CI 0.364-0.831; p = 0.005), multiple numbers of stones (OR 0.254, 95% CI 0.166-0.389; p = < 0.001), the value of parenchymal thickness (OR 0.911, 95% CI 0.882-0.941; p = < 0.001) and more importantly use of anticoagulants/antiplatelets (OR 0.557, 95% CI 0.333-0.933; p = 0.026) appeared to be independent predictors of stone-free status after RIRS. Further evaluation of the data revealed that the cut-off value of the renal parenchymal thickness for an effective stone-free status in a ROC curve analysis was 24.5 with 62.9% sensitivity and 56.8% specificity (area under curve value: 0.654 [95% CI 0.608-0.699, p < 0.001]). The endourologist may be able to make more informed decisions by evaluating renal parenchymal thickness in addition to patient-related factors like anticoagulant use, which we find significantly affects outcomes, along with the stone and renal anatomy-related factors. |
| Anahtar Kelimeler |
| Kidney stones,Retrograde intrarenal surgery,Anticoagulants,Parenchymal thickness |
| Makale Türü | Özgün Makale |
| Makale Alt Türü | SSCI, AHCI, SCI, SCI-Exp dergilerinde yayımlanan tam makale |
| Dergi Adı | UROLITHIASIS |
| Dergi ISSN | 2194-7228 |
| Dergi Tarandığı Indeksler | SCI-Expanded |
| Dergi Grubu | Q2 |
| Makale Dili | İngilizce |
| Basım Tarihi | 01-2023 |
| Cilt No | 51 |
| Sayı | 1 |
| Sayfalar | 1 / 7 |
| Doi Numarası | 10.1007/s00240-022-01404-4 |
| Makale Linki | http://dx.doi.org/10.1007/s00240-022-01404-4 |
| Atıf Sayıları |
