Association of P wave peak time with left ventricular end‐diastolic pressure in patients with hypertension
Yazarlar (10)
Cengiz Burak
Kafkas Üniversitesi, Türkiye
Metin Çağdaş
Kafkas Üniversitesi, Türkiye
Prof. Dr. İbrahim RENCÜZOĞULLARI
Kafkas Üniversitesi, Türkiye
Prof. Dr. Yavuz KARABAĞ
Kafkas Üniversitesi, Türkiye
Tufan Çınar
Muhammed Suleymanoglu
İbrahim Halil Tanboğa
Nişantaşı Üniversitesi, Türkiye
| Makale Türü |
Özgün Makale
(SSCI, AHCI, SCI, SCI-Exp dergilerinde yayınlanan tam makale)
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| Dergi Adı | The Journal of Clinical Hypertension (Q2) | ||
| Dergi ISSN | 1524-6175 Wos Dergi Scopus Dergi | ||
| Dergi Tarandığı Indeksler | SCI-Expanded | ||
| Makale Dili | İngilizce | Basım Tarihi | 04-2019 |
| Cilt / Sayı / Sayfa | 21 / 5 / 608–615 | DOI | 10.1111/jch.13530 |
| Makale Linki | https://onlinelibrary.wiley.com/doi/abs/10.1111/jch.13530 | ||
| Özet |
| Left ventricular diastolic dysfunction (LVDD) is commonly seen in hypertensive patients, and it is associated with increased morbidity and mortality. Hence, the detection of LVDD with a simple, inexpensive, and easy-to-obtain method can contribute to improving patient prognosis. Therefore, we aimed to evaluate whether there was any association between the electrocardiographic P wave peak time (PWPT) and invasively measured left ventricular end-diastolic pressure (LVEDP) in hypertensive patients who had undergone coronary angiography following preliminary diagnosis of coronary artery disease. A total of 78 patients were included in this cross-sectional study. The PWPT was defined as the time from the beginning of the P wave to its peak, and it was calculated from the leads D and V . In all patients, LVEDP was measured in steady state. The PWPT in lead D was significantly longer in patients with high LVEDP; however, there was no significant difference between groups in terms of PWPT in the lead V . In multivariable analysis, PWPT in lead D was found to be independent predictor of increased LVEDP (OR: 1.257, 95% CI: 1.094-1.445; P = 0.001). In receiver operating characteristic curve analysis, the optimal cut-off value of PWPT in the lead D for prediction of elevated LVEDP was 64.8 ms, with a sensitivity of 68.7% and a specificity of 91.3% (area under curve: 0.882, 95% CI: 0.789-0.944, P < 0.001). In conclusion, this study result suggested that prolonged PWPT in the lead D may be an independent predictor of increased LVEDP among hypertensive patients. |
| Anahtar Kelimeler |
| hypertension | left ventricular diastolic dysfunction | left ventricular end-diastolic pressure | P wave peak time |
BM Sürdürülebilir Kalkınma Amaçları
| Atıf Sayıları |