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Association of P wave peak time with left ventricular end‐diastolic pressure in patients with hypertension    
Yazarlar (10)
Cengiz Burak
Kafkas Üniversitesi, Türkiye
Metin Çağdaş
Kafkas Üniversitesi, Türkiye
Prof. Dr. İbrahim RENCÜZOĞULLARI Prof. Dr. İbrahim RENCÜZOĞULLARI
Kafkas Üniversitesi, Türkiye
Doç. Dr. Yavuz KARABAĞ Doç. Dr. Yavuz KARABAĞ
Kafkas Üniversitesi, Türkiye
Dr. Öğr. Üyesi İnanç ARTAÇ Dr. Öğr. Üyesi İnanç ARTAÇ
Türkiye
Mahmut Yesin
Tufan Çınar
İbrahim Yıldız
Muhammed Suleymanoglu
İbrahim Halil Tanboğa
Nişantaşı Üniversitesi, Türkiye
Devamını Göster
Özet
Left ventricular diastolic dysfunction (LVDD) is commonly seen in hypertensive patients, and it is associated with increased morbidity and mortality. Hence, the detection of LVDD with a simple, inexpensive, and easy-to-obtain method can contribute to improving patient prognosis. Therefore, we aimed to evaluate whether there was any association between the electrocardiographic P wave peak time (PWPT) and invasively measured left ventricular end-diastolic pressure (LVEDP) in hypertensive patients who had undergone coronary angiography following preliminary diagnosis of coronary artery disease. A total of 78 patients were included in this cross-sectional study. The PWPT was defined as the time from the beginning of the P wave to its peak, and it was calculated from the leads D and V . In all patients, LVEDP was measured in steady state. The PWPT in lead D was significantly longer in patients with high LVEDP; however, there was no significant difference between groups in terms of PWPT in the lead V . In multivariable analysis, PWPT in lead D was found to be independent predictor of increased LVEDP (OR: 1.257, 95% CI: 1.094-1.445; P = 0.001). In receiver operating characteristic curve analysis, the optimal cut-off value of PWPT in the lead D for prediction of elevated LVEDP was 64.8 ms, with a sensitivity of 68.7% and a specificity of 91.3% (area under curve: 0.882, 95% CI: 0.789-0.944, P < 0.001). In conclusion, this study result suggested that prolonged PWPT in the lead D may be an independent predictor of increased LVEDP among hypertensive patients.
Anahtar Kelimeler
hypertension | left ventricular diastolic dysfunction | left ventricular end-diastolic pressure | P wave peak time
Makale Türü Özgün Makale
Makale Alt Türü SSCI, AHCI, SCI, SCI-Exp dergilerinde yayımlanan tam makale
Dergi Adı The Journal of Clinical Hypertension
Dergi ISSN 1524-6175
Dergi Tarandığı Indeksler SCI-Expanded
Dergi Grubu Q2
Makale Dili İngilizce
Basım Tarihi 04-2019
Cilt No 21
Sayı 5
Sayfalar 608 / 615
Doi Numarası 10.1111/jch.13530
Makale Linki https://onlinelibrary.wiley.com/doi/abs/10.1111/jch.13530