Yazarlar (10) |
![]() Kafkas Üniversitesi, Türkiye |
![]() Kafkas Üniversitesi, Türkiye |
![]() Kafkas Üniversitesi, Türkiye |
![]() Kafkas Üniversitesi, Türkiye |
![]() Türkiye |
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![]() Nişantaşı Üniversitesi, Türkiye |
Özet |
Left ventricular diastolic dysfunction (LVDD) is commonly seen in hypertensive patients, and it is associated with increased morbidity and mortality. Hence, the detection of LVDD with a simple, inexpensive, and easy-to-obtain method can contribute to improving patient prognosis. Therefore, we aimed to evaluate whether there was any association between the electrocardiographic P wave peak time (PWPT) and invasively measured left ventricular end-diastolic pressure (LVEDP) in hypertensive patients who had undergone coronary angiography following preliminary diagnosis of coronary artery disease. A total of 78 patients were included in this cross-sectional study. The PWPT was defined as the time from the beginning of the P wave to its peak, and it was calculated from the leads D and V . In all patients, LVEDP was measured in steady state. The PWPT in lead D was significantly longer in patients with high LVEDP; however, there was no significant difference between groups in terms of PWPT in the lead V . In multivariable analysis, PWPT in lead D was found to be independent predictor of increased LVEDP (OR: 1.257, 95% CI: 1.094-1.445; P = 0.001). In receiver operating characteristic curve analysis, the optimal cut-off value of PWPT in the lead D for prediction of elevated LVEDP was 64.8 ms, with a sensitivity of 68.7% and a specificity of 91.3% (area under curve: 0.882, 95% CI: 0.789-0.944, P < 0.001). In conclusion, this study result suggested that prolonged PWPT in the lead D may be an independent predictor of increased LVEDP among hypertensive patients. |
Anahtar Kelimeler |
hypertension | left ventricular diastolic dysfunction | left ventricular end-diastolic pressure | P wave peak time |
Makale Türü | Özgün Makale |
Makale Alt Türü | SSCI, AHCI, SCI, SCI-Exp dergilerinde yayımlanan tam makale |
Dergi Adı | The Journal of Clinical Hypertension |
Dergi ISSN | 1524-6175 |
Dergi Tarandığı Indeksler | SCI-Expanded |
Dergi Grubu | Q2 |
Makale Dili | İngilizce |
Basım Tarihi | 04-2019 |
Cilt No | 21 |
Sayı | 5 |
Sayfalar | 608 / 615 |
Doi Numarası | 10.1111/jch.13530 |
Makale Linki | https://onlinelibrary.wiley.com/doi/abs/10.1111/jch.13530 |