 
  
		| Yazarlar (10) | 
|  Cengiz Burak Kafkas Üniversitesi, Türkiye | 
|  Metin Çağdaş Kafkas Üniversitesi, Türkiye | 
|  Prof. Dr. İbrahim RENCÜZOĞULLARI Kafkas Üniversitesi, Türkiye | 
|  Prof. Dr. Yavuz KARABAĞ Kafkas Üniversitesi, Türkiye | 
|  Doç. Dr. İnanç ARTAÇ | 
|  Mahmut Yesin | 
|  Tufan Çınar | 
|  İbrahim Yıldız | 
|  Muhammed Suleymanoglu | 
|  İbrahim Halil Tanboğa Nişantaşı Üniversitesi, Türkiye | 
| Özet | 
| Left ventricular diastolic dysfunction (LVDD) is commonly seen in hypertensive patients, and it is associated with increased morbidity and mortality. Hence, the detection of LVDD with a simple, inexpensive, and easy-to-obtain method can contribute to improving patient prognosis. Therefore, we aimed to evaluate whether there was any association between the electrocardiographic P wave peak time (PWPT) and invasively measured left ventricular end-diastolic pressure (LVEDP) in hypertensive patients who had undergone coronary angiography following preliminary diagnosis of coronary artery disease. A total of 78 patients were included in this cross-sectional study. The PWPT was defined as the time from the beginning of the P wave to its peak, and it was calculated from the leads D and V . In all patients, LVEDP was measured in steady state. The PWPT in lead D was significantly longer in patients with high LVEDP; however, there was no significant difference between groups in terms of PWPT in the lead V . In multivariable analysis, PWPT in lead D was found to be independent predictor of increased LVEDP (OR: 1.257, 95% CI: 1.094-1.445; P = 0.001). In receiver operating characteristic curve analysis, the optimal cut-off value of PWPT in the lead D for prediction of elevated LVEDP was 64.8 ms, with a sensitivity of 68.7% and a specificity of 91.3% (area under curve: 0.882, 95% CI: 0.789-0.944, P < 0.001). In conclusion, this study result suggested that prolonged PWPT in the lead D may be an independent predictor of increased LVEDP among hypertensive patients. | 
| Anahtar Kelimeler | 
| hypertension | left ventricular diastolic dysfunction | left ventricular end-diastolic pressure | P wave peak time | 
| Makale Türü | Özgün Makale | 
| Makale Alt Türü | SSCI, AHCI, SCI, SCI-Exp dergilerinde yayınlanan tam makale | 
| Dergi Adı | The Journal of Clinical Hypertension | 
| Dergi ISSN | 1524-6175 Wos Dergi Scopus Dergi | 
| Dergi Tarandığı Indeksler | SCI-Expanded | 
| Dergi Grubu | Q2 | 
| Makale Dili | İngilizce | 
| Basım Tarihi | 04-2019 | 
| Cilt No | 21 | 
| Sayı | 5 | 
| Sayfalar | 608 / 615 | 
| Doi Numarası | 10.1111/jch.13530 | 
| Makale Linki | https://onlinelibrary.wiley.com/doi/abs/10.1111/jch.13530 |