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The C-Reactive Protein to Albumin Ratio Predicts Acute Kidney Injury in Patients With ST-Segment Elevation Myocardial Infarction Undergoing Primary Percutaneous Coronary Intervention    
Yazarlar (10)
Doç. Dr. Yavuz KARABAĞ Doç. Dr. Yavuz KARABAĞ
Kafkas Üniversitesi, Türkiye
Metin Çağdaş
Ibrahim Rencuzogullari
Süleyman Karakoyun
İnanç Artaç
Doğan İliş
Mahmut Yesin
Handan Çiftçi
Halil Ibrahim Erdoğdu
Ibrahim Halil Tanboğa
Devamını Göster
Özet
The relationship between acute kidney injury (AKI) and C-reactive protein (CRP) and albumin has been previously demonstrated in patients with ST elevation myocardial infarction (STEMI) treated with primary percutaneous coronary intervention (pPCI). However, to our knowledge, CRP to albumin ratio (CAR), a newly introduced inflammation-based risk score, has not yet been studied. In this study, we aimed to investigate the possible relationship between the CAR and AKI. A total of 815 consecutive STEMI patients treated with pPCI were reviewed. One hundred ten 110 (13.5%) patients developed AKI in the study population. The subjects were divided into two groups according to AKI development. The in-hospital mortality rate was higher in patients with AKI than those without AKI (15.5% vs. 1.3%; p<0.001). The patients with AKI had significantly higher mean value of CRP and CAR (0.29 [0.16-0.50] vs. 0.55 [0.37-1.05]; p<0.001) and lower mean levels of albumin than those without AKI. Age, diabetes mellitus, haematocrit, left ventricular ejection fraction, hypotension, and CAR (Odds ratio [OR]2.307, 95% confidence interval [CI] 1.397-3.809, p=0.001) were independent predictors of AKI. The CAR may be a useful inflammation-based risk score to predict AKI development in STEMI patients treated with pPCI.
Anahtar Kelimeler
C-Reactive protein | Albumin | C-Reactive protein to albumin ratio | Acute kidney injury | ST elevation myocardial infarction | Primary percutaneous coronary intervention
Makale Türü Özgün Makale
Makale Alt Türü SSCI, AHCI, SCI, SCI-Exp dergilerinde yayımlanan tam makale
Dergi Adı Heart, Lung and Circulation
Dergi ISSN 1443-9506
Dergi Tarandığı Indeksler SCI-Expanded
Dergi Grubu Q3
Makale Dili İngilizce
Basım Tarihi 11-2019
Cilt No 28
Sayı 11
Sayfalar 1638 / 1645
Doi Numarası 10.1016/j.hlc.2018.08.009
Makale Linki https://linkinghub.elsevier.com/retrieve/pii/S1443950618318638