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Association of Syntax Score II with Contrast-induced Nephropathy and Hemodialysis Requirement in Patients with ST Segment Elevation Myocardial Infarction Undergoing Primary Percutaneous Coronary Intervention    
Yazarlar (11)
Prof. Dr. İbrahim RENCÜZOĞULLARI Prof. Dr. İbrahim RENCÜZOĞULLARI
Kafkas Üniversitesi, Türkiye
Metin Çağdaş
Kafkas Üniversitesi, Türkiye
Süleyman Karakoyun
Kafkas Üniversitesi, Türkiye
Doç. Dr. Yavuz KARABAĞ Doç. Dr. Yavuz KARABAĞ
Kafkas Üniversitesi, Türkiye
Mahmut Yesin
Mustafa Ozan Gürsoy
Dr. Öğr. Üyesi İnanç ARTAÇ Dr. Öğr. Üyesi İnanç ARTAÇ
Kafkas Üniversitesi, Türkiye
Dr. Öğr. Üyesi Doğan İLİŞ Dr. Öğr. Üyesi Doğan İLİŞ
Kafkas Üniversitesi, Türkiye
Süleyman Çağan Efe
Kevser Tural
Kafkas Üniversitesi, Türkiye
İbrahim Halil Tanboğa
Türkiye
Devamını Göster
Özet
Contrast-induced nephropathy (CIN) is a common complication of primary percutaneous coronary intervention (pPCI) and is associated with high mortality and morbidity and long hospital stay in patients with ST elevation myocardial infarction (STEMI). The Syntax Score (SS) has previously been studied in STEMI patients, and it was associated with increased CIN development and long-term mortality. This study investigates a possible relationship between CIN development and Syntax Score II (SSII) and compares SS and SSII by assessing CIN risk in STEMI patients treated with pPCI. A total of 1,234 patients who underwent pPCI were divided into 2 groups according to CIN development. Patients with CIN were further divided into 2 groups according to whether or not they required hemodialysis. Reclassification tables, net reclassification improvement, and integrated discriminative improvement methods were used to assess the additive predictive value of SSII for predicting CIN. In the present study, 166 patients (13.5%) had CIN. Although both SS and SSII were significantly higher in CIN patients, only SSII was an independent predictor of CIN (odds ratio [OR], 1.031; 95% confidence interval [CI], 1.012-1.051; p<0.001) and hemodialysis requirement (OR, 1.078; 95% CI, 1.046-1.078; p<0.001). When comparing SSII and SS in their ability to determine CIN risk, we found SSII to have a reclassification improvement of 27.59% (p<0.001) and an integrated discrimination improvement of 9.1% (p<0.001). The combination of clinical and anatomic variables can more accurately identify patients who are at high risk for CIN after pPCI. While SSII is harder to calculate than SS, it provides better prediction for CIN and hemodialysis requirement than SS.
Anahtar Kelimeler
Syntax score II | ST segment elevation myocardial infarction | Contrast induced nephropathy
Makale Türü Özgün Makale
Makale Alt Türü SSCI, AHCI, SCI, SCI-Exp dergilerinde yayımlanan tam makale
Dergi Adı Korean Circulation Journal
Dergi ISSN 1738-5520
Dergi Tarandığı Indeksler SCI-Expanded
Makale Dili İngilizce
Basım Tarihi 01-2018
Cilt No 48
Sayı 1
Sayfalar 59 / 70
Doi Numarası 10.4070/kcj.2017.0058
Makale Linki https://synapse.koreamed.org/DOIx.php?id=10.4070/kcj.2017.0058