Usefulness of The C-Reactive Protein/Albumin Ratio for Predicting No-Reflow in ST-elevation myocardial infarction treated with primary percutaneous coronary intervention
| Yazarlar (11) |
Doç. Dr. Yavuz KARABAĞ
Kafkas Üniversitesi, Türkiye |
Metin Çağdaş
Kafkas Üniversitesi, Türkiye |
Prof. Dr. İbrahim RENCÜZOĞULLARI
Kafkas Üniversitesi, Türkiye |
|
Süleyman Karakoyun
|
|
İnanç Artaç
|
Dr. Öğr. Üyesi Doğan İLİŞ
Kafkas Üniversitesi, Türkiye |
|
Mahmut Yesin
Kafkas Üniversitesi, Türkiye |
|
Öznur Çağdaş Sadioğlu
|
|
Bernas Altıntaş
Türkiye |
|
Cengiz Burak
Kafkas Üniversitesi, Türkiye |
|
İbrahim Halil Tanboğa
Nişantaşı Üniversitesi, Türkiye |
| Özet |
| The ratio of serum C-reactive protein (CRP) to albumin has been proven to be a more accurate indicator than albumin and CRP levels alone in determining the prognosis of patients with cancer and critical illness. The aim of this study was to determine whether the CRP/albumin ratio (CAR) can be linked to imperfect reperfusion that can worsen the prognosis of ST-elevation myocardial infarction (STEMI) in patients treated with primary percutaneous coronary intervention (pPCI). A total of 1217 consecutive STEMI patients who achieved epicardial vessel patency with pPCI were recruited to this study. The study population was divided into 2 groups: reflow (n = 874) and no-reflow (NR) (n = 343) groups. The white blood cell count (WBC), neutrophil-to-lymphocyte ratio (NLR) and CAR (0.03 [0.01-0.04] vs 0.06 [0.03-0.12] (P < .001) were significantly higher in the NR group than in the reflow group, and these factors were found to be independent predictors of NR development. The best cut-off value of CAR predicting NR was 0.59 with a sensitivity of 54.7% and specificity of 86.7. The predictive power of CAR surpassed that of CRP, albumin, WBC count and NLR in the receiver operator curve (ROC) curve comparison. No-reflow can be predicted by systemic inflammation markers including WBC count, NLR and CAR measured from the blood sample obtained on admission. CAR has a higher clinical value than CRP, albumin level, WBC count and NLR in NR prediction. |
| Anahtar Kelimeler |
| albumin | C-reactive protein | C-reactive protein | albumin ratio | no-reflow | ST elevation myocardial infarction |
| Makale Türü | Özgün Makale |
| Makale Alt Türü | SSCI, AHCI, SCI, SCI-Exp dergilerinde yayımlanan tam makale |
| Dergi Adı | European Journal of Clinical Investigation |
| Dergi ISSN | 0014-2972 Wos Dergi Scopus Dergi |
| Dergi Tarandığı Indeksler | SCI-Expanded |
| Makale Dili | İngilizce |
| Basım Tarihi | 06-2018 |
| Cilt No | 48 |
| Sayı | 6 |
| Sayfalar | 12928 / 0 |
| Doi Numarası | 10.1111/eci.12928 |
| Makale Linki | http://doi.wiley.com/10.1111/eci.12928 |
BM Sürdürülebilir Kalkınma Amaçları
| Atıf Sayıları | |
| WoS | 62 |