Assessment of the relationship between C-reactive protein-to-albumin ratio and slow coronary flow in patients with stable angina pectoris
  
Yazarlar (8)
Mahmut Yesin Kafkas Üniversitesi, Türkiye
Metin Çağdaş Kafkas Üniversitesi, Türkiye
Prof. Dr. Yavuz KARABAĞ Kafkas Üniversitesi, Türkiye
Prof. Dr. İbrahim RENCÜZOĞULLARI Kafkas Üniversitesi, Türkiye
Cengiz Burak Kafkas Üniversitesi, Türkiye
Macit Kalçık Hitit Üniversitesi, Türkiye
Mustafa Ozan Gürsoy Türkiye
Makale Türü Özgün Makale (SSCI, AHCI, SCI, SCI-Exp dergilerinde yayınlanan tam makale)
Dergi Adı Coronary Artery Disease (Q4)
Dergi ISSN 0954-6928 Wos Dergi Scopus Dergi
Dergi Tarandığı Indeksler SCI-Expanded
Makale Dili İngilizce Basım Tarihi 01-2019
Cilt / Sayı / Sayfa 30 / 7 / 505–510 DOI 10.1097/MCA.0000000000000773
Makale Linki http://dx.doi.org/10.1097/mca.0000000000000773
Özet
The relationship between severity of coronary artery disease and inflammatory parameters has been previously demonstrated. However, there is a lack of data regarding the role of C-reactive protein-to-albumin ratio (CAR) in slow coronary flow (SCF) in patients with stable angina pectoris (SAP). In this study, we aimed to investigate the relationship between CAR and presence of SCF in patients with SAP. This study enrolled 217 patients undergoing coronary angiography for SAP. SCF was detected in 81 (37.3%) patients, and the control group included 136 patients. All clinical, demographical, and laboratory parameters were entered into a dataset and compared between SCF group and the controls. The mean age of the patients was 66.1 ± 12.1 years (male: 57.1%). C-reactive protein and CAR were significantly higher in patients with SCF compared with controls (P = 0.004 and < 0.001, respectively). Logistic regression analysis demonstrated that high CAR level was an independent determinant of SCF (odds ratio: 1.023; 95% confidence interval: 1.013-1.034; P < 0.001). Higher CAR level may be a valuable predictor of SCF in patients with SAP who undergo coronary angiography. Inflammation may play an important role in the pathogenesis of SCF.
Anahtar Kelimeler
coronary artery disease | C-reactive protein-to-albumin ratio | slow coronary flow | stable angina pectoris