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Association of Serum Osmolarity With Contrast-Induced Nephropathy in Patients With ST-Segment Elevation Myocardial Infarction    
Yazarlar (7)
İbrahim Yıldız
Türkiye
Pınar Özmen Yıldız
Türkiye
Prof. Dr. İbrahim RENCÜZOĞULLARI Prof. Dr. İbrahim RENCÜZOĞULLARI
Kafkas Üniversitesi, Türkiye
Doç. Dr. Yavuz KARABAĞ Doç. Dr. Yavuz KARABAĞ
Kafkas Üniversitesi, Türkiye
Metin Çağdaş
Kafkas Üniversitesi, Türkiye
Cengiz Burak
Kafkas Üniversitesi, Türkiye
Mehmet Sait Gürevin
Türkiye
Devamını Göster
Özet
Contrast-induced nephropathy (CIN) is a prevalent and serious complication after primary percutaneous coronary intervention (pPCI). Although the association between serum osmolarity and chronic kidney disease is well established, its relation to CIN in patients with ST-segment elevation myocardial infarction (STEMI) undergoing pPCI needs to be elucidated. We evaluated the predictive value of serum osmolarity for CIN development in patients with STEMI (n = 768) undergoing pPCI. Serum osmolarity on admission was calculated. The study population was divided into 2 groups according to CIN development, and both groups were compared according to clinical, laboratory, and demographic features, including the serum osmolarity. Serum osmolarity was significantly higher in patients with CIN than in those without CIN (278 [8] vs 284 [9]; = .024). Serum osmolarity (odds ratio: 1.052; 95% confidence interval: 1.018-1.086; = .002), hemoglobin, contrast media volume, creatinine on admission, basal SYNergy between PCI with TAXus and cardiac surgery II score, and left ventricular ejection fraction were found to be independent predictors of CIN. Serum osmolarity (given the simple calculation of this parameter on admission) can be useful to define patients with STEMI undergoing pPCI who are more likely to develop CIN.
Anahtar Kelimeler
contrast-induced nephropathy | ST-elevation myocardial infarction | osmolarity | percutaneous coronary intervention
Makale Türü Özgün Makale
Makale Alt Türü SSCI, AHCI, SCI, SCI-Exp dergilerinde yayımlanan tam makale
Dergi Adı Angiology
Dergi ISSN 0003-3197
Dergi Tarandığı Indeksler SCI
Dergi Grubu Q3
Makale Dili İngilizce
Basım Tarihi 02-2019
Cilt No 70
Sayı 7
Sayfalar 627 / 632
Doi Numarası 10.1177/0003319719826466
Makale Linki http://dx.doi.org/10.1177/0003319719826466