Assessment of Relationship Between C-Reactive Protein to Albumin Ratio and Coronary Artery Disease Severity in Patients With Acute Coronary Syndrome
  
Yazarlar (10)
Metin Çağdaş Kafkas Üniversitesi, Türkiye
Prof. Dr. İbrahim RENCÜZOĞULLARI Kafkas Üniversitesi, Türkiye
Süleyman Karakoyun Kafkas Üniversitesi, Türkiye
Prof. Dr. Yavuz KARABAĞ Kafkas Üniversitesi, Türkiye
Doç. Dr. İnanç ARTAÇ Kafkas Üniversitesi, Türkiye
Dr. Öğr. Üyesi Doğan İLİŞ Kafkas Üniversitesi, Türkiye
Öznur Sadioğlu Çağdaş Kafkas Üniversitesi, Türkiye
Aysu Hayriye Tezcan Kafkas Üniversitesi, Türkiye
Makale Türü Özgün Makale (SSCI, AHCI, SCI, SCI-Exp dergilerinde yayınlanan tam makale)
Dergi Adı Angiology (Q3)
Dergi ISSN 0003-3197 Wos Dergi Scopus Dergi
Dergi Tarandığı Indeksler SCI-Expanded
Makale Dili İngilizce Basım Tarihi 04-2019
Cilt / Sayı / Sayfa 70 / 4 / 361–368 DOI 10.1177/0003319717743325
Makale Linki http://journals.sagepub.com/doi/10.1177/0003319717743325
Özet
The association of coronary artery disease (CAD) severity with increased C-reactive protein (CRP) and decreased albumin levels has been reported. However, to our knowledge, no study has investigated the usefulness of the CRP to albumin ratio (CAR) in predicting intermediate-high SYNergy between Percutaneous Coronary Intervention with TAXus and cardiac surgery (SYNTAX) score (SS) and high SS II. Consecutive patients (n = 344) treated with percutaneous coronary intervention comprised the study population. The study population was divided into 2 groups according to SS >22 and mean SS II values, respectively. Patients with intermediate-high SS and high SS II had higher CAR than patients with low SS and SS II. History of diabetes mellitus, decreased albumin, lower left ventricular ejection fraction, and elevated CAR (odds ratio [OR]: 1.020; 95% confidence interval [CI], 1.009-1.031; P < .001) were independent predictors of high SS. The presence of hypertension, decreased hemoglobin and albumin levels, and increased CAR (OR: 1.014; 95% CI, 1.004-1.023; P < .001) were independent predictors of SS II. In receiver operating characteristic curve comparison, CAR was superior to CRP and albumin in prediction of intermediate-high SS, but only CRP in prediction of high SS II. The CAR calculated from the admission blood samples could be a useful parameter for predicting CAD severity using SS and SS II.
Anahtar Kelimeler
acute coronary syndrome | SYNTAX score | SYNTAX score II | C-reactive protein to albumin ratio