Association of the SYNTAX Score II with cardiac rupture in patients with ST-segment elevation myocardial infarction undergoing a primary percutaneous coronary intervention
  
Yazarlar (11)
Prof. Dr. İbrahim RENCÜZOĞULLARI Kafkas Üniversitesi, Türkiye
Metin Çağdaş Kafkas Üniversitesi, Türkiye
Prof. Dr. Yavuz KARABAĞ Kafkas Üniversitesi, Türkiye
Süleyman Karakoyun Kafkas Üniversitesi, Türkiye
Mustafa Ozan Gürsoy
Süleyman Çağan Efe
Makale Türü Özgün Makale (SSCI, AHCI, SCI, SCI-Exp dergilerinde yayınlanan tam makale)
Dergi Adı Coronary Artery Disease
Dergi ISSN 0954-6928 Wos Dergi Scopus Dergi
Dergi Tarandığı Indeksler SCI
Makale Dili İngilizce Basım Tarihi 01-2018
Cilt / Sayı / Sayfa 29 / 2 / 1–103 DOI 10.1097/MCA.0000000000000571
Makale Linki http://Insights.ovid.com/crossref?an=00019501-900000000-99142
Özet
Despite advances in reperfusion strategies, medical therapy, and emergent surgery, cardiac rupture (CR) is still a major lethal complication. Numerous parameters have been found to be associated with CR development after a primary percutaneous coronary intervention (pPCI). SYNTAX Score (SS) and SYNTAX Score II (SSII) have been studied in ST-segment elevation myocardial infarction (STEMI) patients, and higher scores have been associated with higher mortality. However, the relationship between CR and SSII is unclear. This study investigates the possible relationship between CR and SS, SSII in STEMI patients treated with pPCI. We enrolled 1663 consecutive STEMI patients treated with pPCI, who were divided into two groups according to CR development and compared with each other. Patients were further stratified into the three groups according to their SSII values. In this study, 33 (1.98%) patients developed CR. Both SS and SSII of those with CR were significantly higher than those without (19.27±4.0 vs. 16.40±4.55; P<0.001 and 49.40±16.54 vs. 30.92±11.80; P<0.001, respectively). It was also observed that CR increased gradually according to increasing SSII tertiles. SSII was found to be an independent predictor for CR (odds ratio=1.043, 95% confidence interval: 1.012-1.074; P=0.006). In the long-term follow-up, all-cause mortality was significantly higher in patients with CR than those without (60.6 vs. 8.8%; P<0.001). This study shows that SSII is an independent predictor for CR. Furthermore, patients with CR were associated with a poor prognosis. Closer follow-up of patients with high SSII may be useful in the early detection and treatment of this fatal complication.
Anahtar Kelimeler
cardiac rupture | ST-segment elevation myocardial infarction | SYNTAX Score II | SYNTAX Score