Assessment of the relationship between preprocedural C-reactive protein/albumin ratio and stent restenosis in patients with ST-segment elevation myocardial infarction
Yazarlar (10)
Prof. Dr. İbrahim RENCÜZOĞULLARI
Kafkas Üniversitesi, Türkiye
Prof. Dr. Yavuz KARABAĞ
Kafkas Üniversitesi, Türkiye
Metin Çağdaş
Kafkas Üniversitesi, Türkiye
Süleyman Karakoyun
Türkiye
Sabri Seyis
Türkiye
Mustafa Ozan Gürsoy
Türkiye
Mahmut Yesin
Kafkas Üniversitesi, Türkiye
İbrahim Halil Tanboğa
Nişantaşı Üniversitesi, Türkiye
| Makale Türü |
Özgün Makale
(SSCI, AHCI, SCI, SCI-Exp dergilerinde yayınlanan tam makale)
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| Dergi Adı | Revista Portuguesa de Cardiologia (Q4) | ||
| Dergi ISSN | 0870-2551 Wos Dergi Scopus Dergi | ||
| Dergi Tarandığı Indeksler | SCI-Expanded | ||
| Makale Dili | İngilizce | Basım Tarihi | 04-2019 |
| Cilt / Sayı / Sayfa | 38 / 4 / 269–277 | DOI | 10.1016/j.repc.2018.08.008 |
| Makale Linki | https://linkinghub.elsevier.com/retrieve/pii/S0870255117309782 | ||
| Özet |
| Stent restenosis remains a clinical challenge for patients with ischemic heart disease, since it is associated with repeated coronary interventions as well as higher hospitalization rates and medical costs. Inflammation plays a significant role. Although an association between stent restenosis, increased C-reactive protein (CRP) and decreased albumin levels has been previously reported, no studies have investigated the ability of the CRP/albumin ratio to predict stent restenosis. This retrospective study included 448 patients who had previously undergone primary percutaneous coronary intervention and who were referred for subsequent reintervention due to recurrence of anginal symptoms. The study population was divided into two groups based on whether the patient had developed stent restenosis. They were then stratified into three groups according to their CRP/albumin ratio. Out of 448 patients, stent restenosis was observed in 24.5% (n=110), as determined by coronary angiography. Patients with stent restenosis had a higher CRP/albumin ratio, greater platelet distribution width (PDW), higher CRP levels, and lower levels of both high-density lipoprotein (HDL) cholesterol and serum albumin. The CRP/albumin ratio (OR: 2.289, 95% CI: 1.056-4.959; p=0.036), stent diameter, PDW and HDL cholesterol levels were found to be independent predictors of stent restenosis. A ROC curve comparison demonstrated that the CRP/albumin ratio was a better predictor of restenosis than either albumin and CRP individually, but it was not better than PDW and HDL cholesterol. As a novel inflammation-based risk score, the CRP/albumin ratio may be an easily accessible marker for assessment of stent restenosis risk. |
| Anahtar Kelimeler |
| Stent restenosis | C-reactive protein/albumin ratio | ST-segment elevation myocardial infarction | Inflammation |
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| Atıf Sayıları |