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The effect of circadian blood pressure pattern on presence of fragmented QRS complexes in hypertensive subjects    
Yazarlar (4)
Mehmet Eyuboglu
Türkiye
Doç. Dr. Yavuz KARABAĞ Doç. Dr. Yavuz KARABAĞ
Kafkas Üniversitesi, Türkiye
Suleyman Karakoyun
Türkiye
Bahri Akdeniz
Türkiye
Devamını Göster
Özet
The association of deteriorated circadian blood pressure (BP) variability with presence of fragmented QRS (fQRS) on electrocardiography (ECG) is not clear. The present study aims to evaluate the relationship of BP patterns with presence of fQRS on ECG. A total of 338 consecutive newly diagnosed and never treated hypertensive patients who are without left ventricular hypertrophy and underwent 24-hour ambulatory BP monitoring were enrolled. Patients were classified as dippers, nondippers, and reverse dippers according to ambulatory BP monitoring results. The groups were compared regarding frequency of fQRS on ECG. The frequency of fQRS was significantly higher in reverse dippers compared with dippers (37.7% vs. 20.6%, P = .013). In multivariate logistic regression analysis, nighttime systolic BP was found to be an independent predictor of fQRS on ECG (P < .001, 95% confidence interval = 0.901-0.955). Other predictors of fQRS were daytime diastolic BP and age. Furthermore, fQRS was found to be an independent predictor of reverse dipping BP pattern in hypertensive patients (P = .004, odds ratio: 2.416, 95% confidence interval = 1.327-4.396). In conclusion, as a marker of fibrosis and higher fibrotic burden within myocardium, fQRS may be useful to determine the high-risk hypertensive patients in the absence of left ventricular hypertrophy.
Anahtar Kelimeler
Ambulatory blood pressure monitoring | fibrosis | reverse dipper pattern
Makale Türü Özgün Makale
Makale Alt Türü SSCI, AHCI, SCI, SCI-Exp dergilerinde yayımlanan tam makale
Dergi Adı Journal of the American Society of Hypertension
Dergi ISSN 1933-1711
Dergi Tarandığı Indeksler SCI-Expanded
Makale Dili İngilizce
Basım Tarihi 08-2017
Cilt No 11
Sayı 8
Sayfalar 513 / 518
Doi Numarası 10.1016/j.jash.2017.06.001
Makale Linki https://linkinghub.elsevier.com/retrieve/pii/S1933171117301870