Prevalence of Mitral Valve Prolapse in Residents Living at Moderately High Altitude
  
Yazarlar (5)
Tolga Sinan Güvenç Türkiye
Bahattin Balcı Kafkas Üniversitesi, Türkiye
Makale Türü Açık Erişim Özgün Makale (SSCI, AHCI, SCI, SCI-Exp dergilerinde yayınlanan tam makale)
Dergi Adı Wilderness Environmental Medicine
Dergi ISSN 1080-6032 Wos Dergi Scopus Dergi
Dergi Tarandığı Indeksler SCI-Expanded
Makale Dili İngilizce Basım Tarihi 12-2012
Cilt / Sayı / Sayfa 23 / 4 / 300–306 DOI 10.1016/j.wem.2012.05.017
Makale Linki http://linkinghub.elsevier.com/retrieve/pii/S1080603212001810
Özet
Prolapse of mitral valve leaflets is a frequent disorder and the most common cause of severe mitral regurgitation in western countries. However, little is known about the effects of altitude on mitral valve prolapse. We studied the prevalence and echocardiographic characteristics of mitral valve prolapse at moderately high altitude and sea level. A total of 936 consecutive subjects who were admitted to 2 study institutions at Kars, Turkey (1750 m) and Istanbul, Turkey (7 m) were enrolled in this study to determine prevalence of mitral valve prolapse. Demographic and 2-dimensional echocardiographic characteristics of participants were recorded. Prevalence of mitral valve prolapse was found to be significantly higher in people living at moderate altitude compared with those living at sea level (6.2% vs 2.0%; P = .007). Overall echocardiographic features regarding valve thickness (4.1 ± 0.80 mm vs 3.6 ± 0.66 mm; P = 0.169), maximal valve prolapse (4.6 ± 2.08 mm vs 3.9 ± 0.91 mm; P = .093), and frequency of mitral regurgitation (89% vs 73%; P = .65) were similar between groups, although anterior valve prolapse was seen more frequently at moderate altitude (50% vs 11%; P = .056) and posterior leaflet prolapse was significantly more frequent at sea level (66% vs 10%; P = .002). Mitral valve prolapse is more frequently observed at moderately high altitudes. Further studies are needed to determine clinical importance of our findings.
Anahtar Kelimeler
high altitude | mitral valve prolapse | echocardiography
BM Sürdürülebilir Kalkınma Amaçları
Atıf Sayıları
Prevalence of Mitral Valve Prolapse in Residents Living at Moderately High Altitude

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