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Prevalence of Mitral Valve Prolapse in Residents Living at Moderately High Altitude    
Yazarlar (5)
Tolga Sinan Güvenç
Türkiye
Yiğit Çanga
Türkiye
Doç. Dr. Yavuz KARABAĞ Doç. Dr. Yavuz KARABAĞ
Kafkas Üniversitesi, Türkiye
Kaya Özen
Türkiye
Bahattin Balcı
Kafkas Üniversitesi, Türkiye
Devamını Göster
Özet
Prolapse of mitral valve leaflets is a frequent disorder and the most common cause of severe mitral regurgitation in western countries. However, little is known about the effects of altitude on mitral valve prolapse. We studied the prevalence and echocardiographic characteristics of mitral valve prolapse at moderately high altitude and sea level. A total of 936 consecutive subjects who were admitted to 2 study institutions at Kars, Turkey (1750 m) and Istanbul, Turkey (7 m) were enrolled in this study to determine prevalence of mitral valve prolapse. Demographic and 2-dimensional echocardiographic characteristics of participants were recorded. Prevalence of mitral valve prolapse was found to be significantly higher in people living at moderate altitude compared with those living at sea level (6.2% vs 2.0%; P = .007). Overall echocardiographic features regarding valve thickness (4.1 ± 0.80 mm vs 3.6 ± 0.66 mm; P = 0.169), maximal valve prolapse (4.6 ± 2.08 mm vs 3.9 ± 0.91 mm; P = .093), and frequency of mitral regurgitation (89% vs 73%; P = .65) were similar between groups, although anterior valve prolapse was seen more frequently at moderate altitude (50% vs 11%; P = .056) and posterior leaflet prolapse was significantly more frequent at sea level (66% vs 10%; P = .002). Mitral valve prolapse is more frequently observed at moderately high altitudes. Further studies are needed to determine clinical importance of our findings.
Anahtar Kelimeler
high altitude | mitral valve prolapse | echocardiography
Makale Türü Özgün Makale
Makale Alt Türü SSCI, AHCI, SCI, SCI-Exp dergilerinde yayımlanan tam makale
Dergi Adı Wilderness Environmental Medicine
Dergi ISSN 1080-6032
Dergi Tarandığı Indeksler SCI-Expanded
Makale Dili İngilizce
Basım Tarihi 12-2012
Cilt No 23
Sayı 4
Sayfalar 300 / 306
Doi Numarası 10.1016/j.wem.2012.05.017
Makale Linki http://linkinghub.elsevier.com/retrieve/pii/S1080603212001810
BM Sürdürülebilir Kalkınma Amaçları
Atıf Sayıları
WoS 3
Prevalence of Mitral Valve Prolapse in Residents Living at Moderately High Altitude

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