Human Papilloma Virus‐11 DNA Detection by Graphene‐PAMAM Modified Impedimetric CRISPR‐dCas9 Biosensor
   
Yazarlar (3)
Mehmet Utku Mumcu
Ege University Medical School, Türkiye
Doç. Dr. Zihni Onur UYGUN Kafkas Üniversitesi, Türkiye
Doç. Dr. Zihni Onur UYGUN Kafkas Üniversitesi, Türkiye
Makale Türü Özgün Makale (SSCI, AHCI, SCI, SCI-Exp dergilerinde yayınlanan tam makale)
Dergi Adı Electroanalysis (Q3)
Dergi ISSN 1040-0397 Wos Dergi Scopus Dergi
Dergi Tarandığı Indeksler SCI-Expanded
Makale Dili İngilizce Basım Tarihi 05-2022
Cilt / Sayı / Sayfa 34 / 5 / 830–834 DOI 10.1002/elan.202100536
Makale Linki http://dx.doi.org/10.1002/elan.202100536
Özet
Human Papilloma Virus-11 (HPV-11) is leads to condylomata acuminata (CA), which has commonly known as genital wards that global widespread incidence of 160 to 289 cases per year. In the first-time literature, we detect HPV-11 DNA by using dCas9 modified graphene oxide-PAMAM modified electrodes, impedimetrically. Chronoimpedimetric detection was facilitated the biosensor response time optimization of HPV-11 DNA in 5 minutes. The biosensor has ability to analyze HPV-11 DNA between 50 pM and 1000 pM with good linearity, sensitivity and selectivity. Moreover, we tested our biosensor in real samples matrix by considering recovery of the samples.
Anahtar Kelimeler
biosensor | CRISPR | dCas9 | HPV-11 | chronoimpedance