Human Papilloma Virus‐11 DNA Detection by Graphene‐PAMAM Modified Impedimetric CRISPR‐dCas9 Biosensor
Yazarlar (3)
Mehmet Utku Mumcu
Ege University Medical School, Türkiye
Ege University Medical School, Türkiye
Öğr. Gör. Hilmiye Deniz Ertuğrul Uygun Dokuz Eylül Üniversitesi, Türkiye
Doç. Dr. Zihni Onur UYGUN Kafkas Üniversitesi, Türkiye
| Makale Türü | Özgün Makale (SSCI, AHCI, SCI, SCI-Exp dergilerinde yayınlanan tam makale) | ||
| Dergi Adı | Electroanalysis (Q2) | ||
| Dergi ISSN | 1040-0397 Dergi Bilgileri (2021) | ||
| Dergi Tarandığı Indeksler | SCI-Expanded | ||
| Makale Dili | İngilizce | Basım Tarihi | 12-2021 |
| Cilt / Sayı / Sayfa | 34 / 5 / 830–834 | DOI | 10.1002/elan.202100536 |
| Makale Linki | http://dx.doi.org/10.1002/elan.202100536 | ||
| UAK Araştırma Alanları |
Tıbbi Biyokimya
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| Özet |
| Human Papilloma Virus‐11 (HPV‐11) is leads to condylomata acuminata (CA), which has commonly known as genital wards that global widespread incidence of 160 to 289 cases per year. In the first‐time literature, we detect HPV‐11 DNA by using dCas9 modified graphene oxide‐PAMAM modified electrodes, impedimetrically. Chronoimpedimetric detection was facilitated the biosensor response time optimization of HPV‐11 DNA in 5 minutes. The biosensor has ability to analyze HPV‐11 DNA between 50 pM and 1000 pM with good linearity, sensitivity and selectivity. Moreover, we tested our biosensor in real samples matrix by considering recovery of the samples. |
| Anahtar Kelimeler |
| biosensor | chronoimpedance | CRISPR | dCas9 | HPV-11 |
BM Sürdürülebilir Kalkınma Amaçları
| Atıf Sayıları | |
| Web of Science | 2 |
| Scopus | 4 |
| Google Scholar | 9 |