Yazarlar |
Mehmet Utku Mumcu
Türkiye |
Hilmiye Deniz Ertuğrul Uygun
Dokuz Eylül Üniversitesi, Türkiye |
Doç. Dr. Zihni Onur UYGUN
Türkiye |
Özet |
Human Papilloma Virus-11 (HPV-11) is leads to condylomata acuminata (CA), which has commonly known as genital wards that global widespread incidence of 160 to 289 cases per year. In the first-time literature, we detect HPV-11 DNA by using dCas9 modified graphene oxide-PAMAM modified electrodes, impedimetrically. Chronoimpedimetric detection was facilitated the biosensor response time optimization of HPV-11 DNA in 5 minutes. The biosensor has ability to analyze HPV-11 DNA between 50 pM and 1000 pM with good linearity, sensitivity and selectivity. Moreover, we tested our biosensor in real samples matrix by considering recovery of the samples. |
Anahtar Kelimeler |
biosensor | CRISPR | dCas9 | HPV-11 | chronoimpedance |
Makale Türü | Özgün Makale |
Makale Alt Türü | SSCI, AHCI, SCI, SCI-Exp dergilerinde yayımlanan tam makale |
Dergi Adı | ELECTROANALYSIS |
Dergi ISSN | 1040-0397 |
Dergi Tarandığı Indeksler | SCI-Expanded |
Dergi Grubu | Q3 |
Makale Dili | İngilizce |
Basım Tarihi | 05-2022 |
Cilt No | 34 |
Sayı | 5 |
Sayfalar | 830 / 834 |
Doi Numarası | 10.1002/elan.202100536 |
Makale Linki | http://dx.doi.org/10.1002/elan.202100536 |