| Yazarlar (9) |
Bettina Schelkle
Cardiff University, İngiltere |
|
Young Choi
Battelle, Amerika Birleşik Devletleri |
|
Leslie W. Baillie
Cardiff University, İngiltere |
|
William Richter
Battelle, Amerika Birleşik Devletleri |
Prof. Dr. Fatih BÜYÜK
Kafkas Üniversitesi, Türkiye |
|
Elif Celik
Kafkas Üniversitesi, Veteriner Fakültesi, Türkiye |
|
Morgan Wendling
Battelle, Amerika Birleşik Devletleri |
|
Mitat Sahin
Kafkas Üniversitesi, Veteriner Fakültesi, Türkiye |
|
Theresa Gallagher
Avila Scientific, Amerika Birleşik Devletleri |
| Özet |
| Remediation of Bacillus anthracis-contaminated soil is challenging and approaches to reduce overall spore levels in environmentally contaminated soil or after intentional release of the infectious disease agent in a safe, low-cost manner are needed. B. anthracis spores are highly resistant to biocides, but once germinated they become susceptible to traditional biocides or potentially even natural predators such as nematodes in the soil environment. Here, we describe a two-step approach to reducing B. anthracis spore load in soil during laboratory trials, whereby germinants and Caenorhabditis elegans nematodes are applied concurrently. While the application of germinants reduced B. anthracis spore load by up to four logs depending on soil type, the addition of nematodes achieved a further log reduction in spore count. These laboratory based results suggest that the combined use of nematodes and germinants could represent a promising approach for the remediation of B. anthracis spore contaminated soil. Originality-Significance Statement: This study demonstrates for the first time the successful use of environmentally friendly decontamination methods to inactivate Bacillus anthracis spores in soil using natural predators of the bacterium, nematode worms. |
| Anahtar Kelimeler |
| Anthrax | Caenorhabditis elegans N2 | Environmentally friendly | Inosine | L-alanine | Remediation |
| Makale Türü |
Diğer (Teknik, not, yorum, vaka takdimi, editöre mektup, özet, kitap krıtiği,
araştırma notu, bilirkişi raporu ve benzeri)
|
| Makale Alt Türü | Diğer hakemli uluslararası dergilerde yayınlanan teknik not, editöre mektup, tartışma, vaka takdimi ve özet türünden makale |
| Dergi Adı | Frontiers in Microbiology |
| Dergi ISSN | 1664-302X Wos Dergi Scopus Dergi |
| Dergi Tarandığı Indeksler | Google Scholar (scholar.google.com) and RISC (elibrary.ru) |
| Makale Dili | İngilizce |
| Basım Tarihi | 10-2018 |
| Cilt No | 8 |
| Doi Numarası | 10.3389/fmicb.2017.02601 |
