| Yazarlar |
Rıza Durmaz
Yıldırım Beyazıt Üniversitesi, Türkiye |
|
Mehmet Doğanay
Erciyes Üniversitesi, Türkiye |
Prof. Dr. Mitat ŞAHİN
Kafkas Üniversitesi, Türkiye |
|
Duygu Percin
Türkiye |
|
Mustafa Kasım Karahocagil
Yüzüncü Yıl Üniversitesi, Türkiye |
|
Uner Kayabas
Türkiye |
|
Barıs Otlu
Türkiye |
|
Alper Karagoz
Türkiye |
|
Fatih Büyük
Türkiye |
Prof. Dr. Özgür ÇELEBİ
Kafkas Üniversitesi, Türkiye |
|
Zulal Ozturk
Türkiye |
|
Mustafa Ertek
Türkiye |
|
Anthrax Study Group
Türkiye |
Prof. Dr. Fatih BÜYÜK
Kafkas Üniversitesi, Türkiye |
| Özet |
| The main perspective of this study was to determine cross-transmissions amongst anthrax cases and provide detailed information regarding the genotypes of Bacillus anthracis isolates circulating in Turkey. A total of 251 B. anthracis isolates were obtained from human (93 isolates), animal (155 isolates), and environmental (three isolates) samples in various provinces of Turkey. All isolates were susceptible to quinolones, vancomycin, tigecycline, and linezolid, but not to ceftriaxone. Excluding human isolates, one of the animal isolates was found to be resistant to penicillin, erythromycin, and doxycycline. Multiple-locus variable-number tandem repeats analysis including 8 loci (MLVA8) revealed 12 genotypes, in which genotype 43 was observed at the highest frequency (41.8 %), followed by genotype 35 (25.5 %) and genotype 27 (10.4 %). Major subtype A3.a was the predominant cluster, including 86.8 % of the isolates. The MLVA25 analysis for the 251 isolates yielded 62 different genotypes, 33 of which had only one isolate, while the remaining 29 genotypes had 2 to 43 isolates, with a total of 218 isolates (86.9 %). These findings indicate very high cross-transmission rates within anthrax cases in Turkey. The genotypes diagnosed in Turkey are populated in the A major cluster. Penicillin prescribed as the first-choice antibiotic for the treatment of anthrax is still effective. © Springer-Verlag 2012. |
| Anahtar Kelimeler |
| Makale Türü | Özgün Makale |
| Makale Alt Türü | SSCI, AHCI, SCI, SCI-Exp dergilerinde yayımlanan tam makale |
| Dergi Adı | European Journal of Clinical Microbiology & Infectious Diseases |
| Dergi ISSN | 0934-9723 |
| Dergi Tarandığı Indeksler | SSCI |
| Makale Dili | İngilizce |
| Basım Tarihi | 05-2012 |
| Cilt No | 31 |
| Sayı | 10 |
| Sayfalar | 2783 / 2790 |
| Doi Numarası | DOI 10.1007/s10096-012-1628-4 |
| Makale Linki | http://abs.kafkas.edu.tr/upload/466/yayin_riza.pdf |
| Atıf Sayıları | |
| SCOPUS | 26 |
