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The relationship between plasma atherogenic index and long-term outcomes after endovascular intervention in superficial femoral artery lesions        
Yazarlar
Mehmet Altunova
Dr. Öğr. Üyesi Muammer KARAKAYALI Dr. Öğr. Üyesi Muammer KARAKAYALI
Kafkas Üniversitesi, Türkiye
Ceren Yıldırım
Seda Tükenmez Karakurt
Gökhan Demirci
Türkiye
Serkan Aslan
Türkiye
Arda Güler
Türkiye
Ali Evsen
Türkiye
Mehmet Ertürk
Türkiye
Özet
Objectives: Peripheral arterial disease (PAD) results from the systemic atherosclerotic process. In this study, we aimed to determine the relationship between plasma atherogenic index (AIP), a ratio of molar concentrations of triglycerides to HDL-cholesterol, and long-term outcomes after endovascular therapy (EVT) in patients with superficial femoral artery (SFA) stenosis. Methods: We retrospectively evaluated 673 patients who underwent EVT for PAD in our tertiary center between January 2015 and December 2020. In the receiver operating characteristic (ROC) curve analysis, the AIP value with the optimum cutoff value was determined as 0.576 to detect the presence of major adverse limb events (MALEs). Patients were divided into two groups according to low AIP (<0.576 as group 1) and high AIP (>0.576 as group 2). Results: Among the major endpoints, long-term restenosis rates were significantly higher in patients in the high-AIP group than in the low-AIP group (p<.001). The lower extremity amputation rate was not statistically significant between the two groups. All-cause mortality rate (54 (31.6) versus 117 (68.4), p<.001) was significantly higher in patients in the high-AIP group than in the low-AIP group. In addition, the MALE rate (94 (29.2) versus 218 (62.1), p<.001) was significantly higher in patients in the high-AIP group than in those in the low-AIP group. Conclusions: In conclusion, we found that AIP is a significant independent predictor of long-term MALE in patients who underwent EVT for SFA.
Anahtar Kelimeler
major adverse limb events | peripheral arterial disease | Plasma atherogenic index
Makale Türü Özgün Makale
Makale Alt Türü SSCI, AHCI, SCI, SCI-Exp dergilerinde yayımlanan tam makale
Dergi Adı VASCULAR
Dergi ISSN 1708-5381
Dergi Tarandığı Indeksler SCI-Expanded
Dergi Grubu Q4
Makale Dili İngilizce
Basım Tarihi 04-2024
Cilt No 32
Sayı 2
Sayfalar 310 / 319
Doi Numarası 10.1177/17085381231193494
Makale Linki http://dx.doi.org/10.1177/17085381231193494