Yazarlar |
Aksak Karamese Selina
|
Doç. Dr. Murat KARAMEŞE
Kafkas Üniversitesi |
Karakus Emre
|
Ismail Malkoc
|
Unal Bunyami
|
Gundogdu Cemal
|
Özet |
Estrogen is one of the most important regulators of neuron function. There is a broad consensus that a loss of estrogen is associated with neurodegeneration in the hippocampus which leads to cognitive impairment. Hematopoietic-Pbx-interaction-protein (HPIP) is a novel scaffolding protein which interacts with microtubules and estrogen receptors. In this study, we investigated the presence and role of HPIP in hippocampal neurons and examined the relationship between estrogen receptors and microtubule damage in post-menopausal rat brains. |
Anahtar Kelimeler |
Axonal neurodegeneration,Estrogen receptors,HPIP,Microtubule,Ovariectomy |
Makale Türü | Özgün Makale |
Makale Alt Türü | ESCI dergilerinde yayımlanan tam makale |
Dergi Adı | ACTA HISTOCHEMICA |
Dergi ISSN | 0065-1281 |
Makale Dili | İngilizce |
Basım Tarihi | 1-2015 |
Cilt No | 117 |
Sayı | 8 |
Sayfalar | 747 / 751 |
Doi Numarası | 10.1016/j.acthis.2015.08.005 |