| Yazarlar (11) | 
|  Dr. Öğr. Üyesi Nail Tekin ÖNDER Kafkas Üniversitesi, Türkiye | 
|  Dr. Öğr. Üyesi Yusuf Umut BATI Kafkas Üniversitesi, Türkiye | 
|  Dr. Öğr. Üyesi Taygun GÖKDEMİR Kafkas Üniversitesi, Türkiye | 
|  Muhammet Can Kılıç | 
|  Oğuzhan Şahin | 
|  Prof. Dr. Metin ÖĞÜN Kafkas Üniversitesi, Türkiye | 
|  Doç. Dr. Enes AKYÜZ Kafkas Üniversitesi, Türkiye | 
|  Prof. Dr. Mushap KURU Kafkas Üniversitesi, Türkiye | 
|  Prof. Dr. Ali Haydar KIRMIZIGÜL Kafkas Üniversitesi, Türkiye | 
|  Prof. Dr. Savaş YILDIZ Kafkas Üniversitesi, Türkiye | 
|  Prof. Dr. Yavuz ÖZTÜRKLER Kafkas Üniversitesi, Türkiye | 
| Özet | 
| This study aimed to investigate the stress-related changes that may occur in sheep following non-surgical cervical line passage. A total of 20 sheep underwent transcervical transition, and their heart rate, respiratory rate, body temperature, and blood samples were collected at specific time points: 1 h prior to the procedure, immediately after the procedure, and at 1, 2, 3, 4 and 5 h post-procedure. The study found that there was a statistically significant decrease in body temperature immediately after the procedure (p < .05); however, there were no significant differences in body temperature at other time points (p > .05). Respiratory rate remained similar throughout the study, and no significant differences were observed (p > .05). On the other hand, there was a significant increase in heart rate at the 1-h mark after the procedure (p < .05), which subsequently decreased to a similar level as the control group at the 4-h mark after the procedure (p > .05). The cortisol levels increased significantly after the application (p < .05) but decreased to a level similar to the control after 1 h (p > .05). The level of nitric oxide increased significantly in the first hour (p < .05) and decreased by the 5th hour (p < .05). There was a significant increase in malondialdehyde (MDA) and total oxidant capacity (TOC) levels 2 h after the application (p < .05), but this increase ceased at the 4th and 5th hours for MDA (p > .05) and at the 3rd, 4th and 5th hours for TOC (p > .05). The total antioxidant capacity decreased after the 2nd hour of application (p < .05) but remained similar at the fourth and 5th hours (p > .05). In conclusion, based on the cortisol data, transcervical manipulations create short-term stress. Therefore, it may be necessary to use various antioxidants before such procedures to reduce the effects of oxidative stress. | 
| Anahtar Kelimeler | 
| ewe | oxidative stress | transcervical | 
| Makale Türü | Özgün Makale | 
| Makale Alt Türü | SSCI, AHCI, SCI, SCI-Exp dergilerinde yayınlanan tam makale | 
| Dergi Adı | Reproduction in Domestic Animals | 
| Dergi ISSN | 0936-6768 Wos Dergi Scopus Dergi | 
| Dergi Tarandığı Indeksler | SCI-Expanded | 
| Dergi Grubu | Q2 | 
| Makale Dili | İngilizce | 
| Basım Tarihi | 06-2023 | 
| Cilt No | 58 | 
| Sayı | 6 | 
| Sayfalar | 877 / 881 | 
| Doi Numarası | 10.1111/rda.14361 | 
| Makale Linki | http://dx.doi.org/10.1111/rda.14361 |