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The Anti-SARS-CoV-2 IgG Antibody Response of Participants Vaccinated with Different Vaccine Combination   
Yazarlar (2)
Doç. Dr. Murat KARAMEŞE Doç. Dr. Murat KARAMEŞE
Kafkas Üniversitesi, Türkiye
Dr. Öğr. Üyesi Abdullah GÜMÜŞ Dr. Öğr. Üyesi Abdullah GÜMÜŞ
Kafkas Üniversitesi, Türkiye
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Özet
Introduction In current literature, there are lots of description about the new Coronavirus, named as SARS-CoV-2 by World Health Organization (WHO). Basically, SARS-CoV-2 has been identified as the etiological agent of COVID-19 disease which was reported a group of patients with pneumonia of unknown cause in Wuhan, China, in December 2019. In this work, our aim was to investigate the anti-S1 IgG response that occurs after different kinds and different doses of SARS-CoV-2 vaccines and the demographic characteristics of participants.Materials and Methods A total of 299 participants were included in this study to detect the Anti-SARS-CoV-2 IgG antibody. The only inclusion criteria for this study were being vaccinated minimum 2-doses of any SARS-CoV-2 vaccine. For detecting the antibody levels of participants, Anti-SARS-CoV-2 ELISA (IgG) test kit which applies a recombinant S1 subunit of the SARS-CoV-2 spike protein, enabling detection of IgG antibodies was used.Results Out of 299 individuals, 128 (42.8%) were male and 171 (57.2%) were female in our study. The mean age of individuals 35.11±8.13 (minimum: 19 and maximum: 59). The lowest antibody levels were belong to Group 2 and Group 3 (138.66±25.41, and 82.09±63.42 IU/ml, respectively), while the highest antibody levels were belong to Group 6 (239.35±18.73 IU/ml).Discussion According to our result, a significantly higher humoral immunogenicity of the SARS-CoV-2 BioNTech compared with the CoronaVac vaccine. A significant increase in serological response was achieved with the 3rd or 4th dose of vaccine; however, it had better to be vaccinated with BioNTech …
Anahtar Kelimeler
Makale Türü Özgün Makale
Makale Alt Türü Diğer hakemli uluslarası dergilerde yayınlanan tam makale
Dergi Adı Eurasian Journal of Molecular and Biochemical Sciences
Dergi ISSN 2822-4019
Dergi Tarandığı Indeksler Index Copernicus
Makale Dili İngilizce
Basım Tarihi 04-2023
Cilt No 2
Sayı 1
Sayfalar 30 / 34
Makale Linki chrome-extension://efaidnbmnnnibpcajpcglclefindmkaj/https://dergipark.org.tr/en/download/article-file/3019215
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