| Yazarlar |
Dr. Öğr. Üyesi Nurullah ÇİFTÇİ
Türkiye |
İdris Sargın
Selçuk Üniversitesi, Türkiye |
|
Gülşin Arslan
Selçuk Üniversitesi, Türkiye |
|
Serdar Karakurt
Türkiye |
|
Uğur Arslan
Selçuk Üniversitesi, Türkiye |
| Özet |
| This study aimed to investigate the antimicrobial effect of gold nanoparticles capped with meropenem and imipenem against various strains and to evaluate the cytotoxic effect of gold nanoparticles on healthy human colon epithelial cells. Gold nanoparticles were synthesized via the Turkevich method and tested for antimicrobial effects using broth microdilution. Cell culture studies were performed using a cytotoxicity assay with alamarBlue™. Nanoparticles (10-20 nm) with antibiotic coating were more effective against , spp. and than pure antibiotics. They had a cytotoxic effect on cells at high concentrations but were safe at low concentrations. |
| Anahtar Kelimeler |
| antimicrobial resistance | cell culture | gold nanoparticles | imipenem | meropenem |
| Makale Türü | Özgün Makale |
| Makale Alt Türü | SSCI, AHCI, SCI, SCI-Exp dergilerinde yayımlanan tam makale |
| Dergi Adı | NANOMEDICINE |
| Dergi ISSN | 1743-5889 |
| Dergi Tarandığı Indeksler | SCI-Expanded |
| Dergi Grubu | Q2 |
| Makale Dili | Türkçe |
| Basım Tarihi | 10-2023 |
| Cilt No | 18 |
| Sayı | 24 |
| Sayfalar | 1719 / 1731 |
| Doi Numarası | 10.2217/nnm-2023-0223 |
| Makale Linki | http://dx.doi.org/10.2217/nnm-2023-0223 |
| Atıf Sayıları | |
| WoS | 2 |
