Yazarlar |
Murat KARAMEŞE
Kafkas Üniversitesi, Türkiye |
Dr. Öğr. Üyesi Abdullah GÜMÜŞ
Kafkas Üniversitesi, Türkiye |
Eray ATALAY
Kafkas Üniversitesi, Türkiye |
Emin Ediz Tütüncü
Sağlık Bilimleri Üniversitesi, Türkiye |
Özet |
Our aim was to investigate the differences between healthy people and COVID-19 patients in terms of some immunological biomolecules, especially including those related to the inflammation process. A total of 180 participants (90 healthy controls and 90 COVID-19 patients) were included. The expression levels of eight different inflammation-related biomolecules were measured by the ELISA technique. The mean levels of ACE2, ANG1-7, GAL3, GAL9, SCUBE1, SCUBE2 and SCUBE3 were elevated in COVID-19 patients when compared with healthy controls, while the mean level of GAL2 was lower in COVID-19 patients than controls. To understand the cytokine storm mechanism and related parameters, more detailed studies should be performed investigating more related biomolecules and related signaling pathways. |
Anahtar Kelimeler |
ACE2 | COVID-19 | galectins | inflammation | SARS-CoV-2 | SCUBE |
Makale Türü | Özgün Makale |
Makale Alt Türü | SSCI, AHCI, SCI, SCI-Exp dergilerinde yayımlanan tam makale |
Dergi Adı | FUTURE MICROBIOLOGY |
Dergi ISSN | 1746-0913 |
Dergi Tarandığı Indeksler | SCI-Expanded |
Dergi Grubu | Q3 |
Makale Dili | Türkçe |
Basım Tarihi | 12-2023 |
Cilt No | 18 |
Sayı | 18 |
Sayfalar | 1329 / 1337 |
Doi Numarası | 10.2217/fmb-2023-0099 |
Makale Linki | http://dx.doi.org/10.2217/fmb-2023-0099 |