Assessment of the levels of some prognostic biomolecules (galectins, ACE2, SCUBE1/2/3) in COVID-19 patients
Yazarlar (4)
Doç. Dr. Murat KARAMEŞE Kafkas Üniversitesi, Türkiye
Dr. Öğr. Üyesi Abdullah GÜMÜŞ Kafkas Üniversitesi, Türkiye
Doç. Dr. Eray ATALAY Kafkas Üniversitesi, Türkiye
Emin Ediz Tütüncü
Sağlık Bilimleri Üniversitesi, Türkiye
Sağlık Bilimleri Üniversitesi, Türkiye
| Makale Türü | Özgün Makale (SSCI, AHCI, SCI, SCI-Exp dergilerinde yayınlanan tam makale) | ||
| Dergi Adı | FUTURE MICROBIOLOGY (Q3) | ||
| Dergi ISSN | 1746-0913 Dergi Bilgileri (2023) | ||
| Dergi Tarandığı Indeksler | SCI-Expanded | ||
| Makale Dili | Türkçe | Basım Tarihi | 12-2023 |
| Cilt / Sayı / Sayfa | 18 / 18 / 1329–1337 | DOI | 10.2217/fmb-2023-0099 |
| Makale Linki | http://dx.doi.org/10.2217/fmb-2023-0099 | ||
| UAK Araştırma Alanları |
Tıbbi Mikrobiyoloji
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| Özet |
| Our aim was to investigate the differences between healthy people and COVID-19 patients in terms of some immunological biomolecules, especially including those related to the inflammation process. A total of 180 participants (90 healthy controls and 90 COVID-19 patients) were included. The expression levels of eight different inflammation-related biomolecules were measured by the ELISA technique. The mean levels of ACE2, ANG1-7, GAL3, GAL9, SCUBE1, SCUBE2 and SCUBE3 were elevated in COVID-19 patients when compared with healthy controls, while the mean level of GAL2 was lower in COVID-19 patients than controls. To understand the cytokine storm mechanism and related parameters, more detailed studies should be performed investigating more related biomolecules and related signaling pathways. |
| Anahtar Kelimeler |
| ACE2 | COVID-19 | galectins | inflammation | SARS-CoV-2 | SCUBE |
BM Sürdürülebilir Kalkınma Amaçları
| Atıf Sayıları | |
| Web of Science | 2 |