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The effect of idiopathic premature ventricular complexes on left ventricular ejection fraction    
Yazarlar (25)
Bernas Altıntaş
Flora Özkalaycı
Göksel Çinier
Türkiye
İlyas Kaya
Sağlık Bilimleri Üniversitesi, Türkiye
Adem Aktan
Ayhan Küp
Raşit Onuk
Sevgi Özcan
Abdulkadir Uslu
Abdurrahman Akyüz
Adem Atıcı
İstanbul Medeniyet Üniversitesi, Türkiye
Selim Ekinci
Halil Akın
Mehmet Fatih Yılmaz
Şahbender Koç
Veysel Ozan Tanık
Hazar Harbalıoğlu
Hasan Ali Barman
Abdülmecit Afşin
Ayça Gümüşdağ
Kafkas Üniversitesi, Türkiye
Hayrudin Alibaşiç
Doç. Dr. Yavuz KARABAĞ Doç. Dr. Yavuz KARABAĞ
Kafkas Üniversitesi, Türkiye
Murat Cap
Erkan Baysal
İbrahim Halil Tanboğa
Nişantaşı Üniversitesi, Türkiye
Devamını Göster
Özet
Current literature lacks a definitive threshold of idiopathic premature ventricular complex (PVC) burden for predicting cardiomyopathy (CMP). The main objective of the present study was to evaluate relationship between the PVC burden and left ventricular ejection fraction (LVEF). This multicenter, cross-sectional study included 341 consecutive patients with more than 1,000 idiopathic PVC in 24 hr of Holter monitoring admitted to the cardiology clinics between January 2019 and May 2019 in the nineteen different centers. The primary outcome was the LVEF measured during the echocardiographic examination. Overall, the median age was 50 (38-60) and 139 (49.4%) were female. Percentage of median PVC burden was 9% (IQR: 4%-17.4%). Median LVEF was found 60% (55-65). We used proportional odds logistic regression method to examine the relationship between continuous LVEF and candidate predictors. Increase in PVC burden (%) (regression coefficient (RE) -0.644 and 95% CI -1.063, -0.225, p < .001), PVC QRS duration (RE-0.191 and 95% CI -0.529, 0.148, p = .049), and age (RE-0.249 and 95% CI -0.442, -0.056, p = .018) were associated with decrease in LVEF. This inverse relationship between the PVC burden and LVEF become more prominent when PVC burden was above 5%. A nomogram developed to estimate the individual risk for decrease in LVEF. Our study showed that increase in PVC burden %, age, and PVC QRS duration were independently associated with decrease in LVEF in patients with idiopathic PVC. Also, inverse relationship between PVC burden and LVEF was observed in lower PVC burden than previously known.
Anahtar Kelimeler
cardiomyopathy | left ventricular ejection fraction | premature ventricular complexes
Makale Türü Özgün Makale
Makale Alt Türü SSCI, AHCI, SCI, SCI-Exp dergilerinde yayımlanan tam makale
Dergi Adı ANNALS OF NONINVASIVE ELECTROCARDIOLOGY
Dergi ISSN 1082-720X
Dergi Tarandığı Indeksler SCI-Expanded
Makale Dili İngilizce
Basım Tarihi 03-2020
Cilt No 25
Sayı 2
Doi Numarası 10.1111/anec.12702