Yazarlar (8) |
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![]() Kafkas Üniversitesi, Türkiye |
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![]() Kafkas Üniversitesi, Türkiye |
![]() Kafkas Üniversitesi, Türkiye |
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Özet |
Although the prognostic efficacy of C-reactive protein (mg/L) and albumin levels (g/L) has been previously associated with poor prognosis in ST elevation myocardial infarction (STEMI), to the best of our knowledge, the prognostic efficacy of C-reactive protein/Albumin ratio (CAR) (mg/g) has not been investigated yet. Thus, this study aimed to investigate the potential efficacy of the CAR in predicting prognosis in STEMI patients. We conducted a detailed investigation of 2437 patients with first STEMI treated with a primary percutaneous coronary intervention. After evaluation regarding to exclusion criteria, 2243 patients were found to be eligible for analysis. The mean follow-up of the study was 34 ± 15 months. The median CAR value of the study population was 2.70 (range: 1.44-4.76), and the patients were divided into three tertiles according to their CAR values. Kaplan-Meier survival analysis showed significantly lower in-hospital and long-term survival rates for the patients in a high CAR tertile. In addition, the CAR was found to be an independent predictor of all-cause mortality (Hazards ratio: 1.033, 95% Confidence Interval: 1.007-1.061, p = .033), and the prognostic performance of the CAR was superior to that of C-reactive protein, albumin, and neutrophil to lymphocyte ratio in the receiver operating characteristic curve comparison. The CAR, a newly introduced inflammation-based risk index, was found to be a potentially useful prognostic tool for predicting a poor prognosis in STEMI patients. However, this finding needs to be validated in the future prospective studies. |
Anahtar Kelimeler |
ST elevation myocardial infarction | C-reactive protein to Albumin ratio | all-cause mortality |
Makale Türü | Özgün Makale |
Makale Alt Türü | SSCI, AHCI, SCI, SCI-Exp dergilerinde yayımlanan tam makale |
Dergi Adı | Scandinavian Cardiovascular Journal |
Dergi ISSN | 1401-7431 |
Dergi Tarandığı Indeksler | SCI-Expanded |
Dergi Grubu | Q4 |
Makale Dili | İngilizce |
Basım Tarihi | 04-2019 |
Cilt No | 53 |
Sayı | 2 |
Sayfalar | 83 / 90 |
Doi Numarası | 10.1080/14017431.2019.1590628 |
Makale Linki | https://www.tandfonline.com/doi/full/10.1080/14017431.2019.1590628 |