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Prognostic efficacy of C-reactive protein/albumin ratio in ST elevation myocardial infarction    
Yazarlar (8)
Tufan Çinar
Metin Çağdaş
Kafkas Üniversitesi, Türkiye
İbrahim Rencüzoğullari
Süleyman Karakoyun
Doç. Dr. Yavuz KARABAĞ Doç. Dr. Yavuz KARABAĞ
Kafkas Üniversitesi, Türkiye
Mahmut Yesin
Kafkas Üniversitesi, Türkiye
Öznur Sadioğlu Çağdaş
Halil İbrahim Tanboğa
Devamını Göster
Özet
Although the prognostic efficacy of C-reactive protein (mg/L) and albumin levels (g/L) has been previously associated with poor prognosis in ST elevation myocardial infarction (STEMI), to the best of our knowledge, the prognostic efficacy of C-reactive protein/Albumin ratio (CAR) (mg/g) has not been investigated yet. Thus, this study aimed to investigate the potential efficacy of the CAR in predicting prognosis in STEMI patients. We conducted a detailed investigation of 2437 patients with first STEMI treated with a primary percutaneous coronary intervention. After evaluation regarding to exclusion criteria, 2243 patients were found to be eligible for analysis. The mean follow-up of the study was 34 ± 15 months. The median CAR value of the study population was 2.70 (range: 1.44-4.76), and the patients were divided into three tertiles according to their CAR values. Kaplan-Meier survival analysis showed significantly lower in-hospital and long-term survival rates for the patients in a high CAR tertile. In addition, the CAR was found to be an independent predictor of all-cause mortality (Hazards ratio: 1.033, 95% Confidence Interval: 1.007-1.061, p = .033), and the prognostic performance of the CAR was superior to that of C-reactive protein, albumin, and neutrophil to lymphocyte ratio in the receiver operating characteristic curve comparison. The CAR, a newly introduced inflammation-based risk index, was found to be a potentially useful prognostic tool for predicting a poor prognosis in STEMI patients. However, this finding needs to be validated in the future prospective studies.
Anahtar Kelimeler
ST elevation myocardial infarction | C-reactive protein to Albumin ratio | all-cause mortality
Makale Türü Özgün Makale
Makale Alt Türü SSCI, AHCI, SCI, SCI-Exp dergilerinde yayımlanan tam makale
Dergi Adı Scandinavian Cardiovascular Journal
Dergi ISSN 1401-7431
Dergi Tarandığı Indeksler SCI-Expanded
Dergi Grubu Q4
Makale Dili İngilizce
Basım Tarihi 04-2019
Cilt No 53
Sayı 2
Sayfalar 83 / 90
Doi Numarası 10.1080/14017431.2019.1590628
Makale Linki https://www.tandfonline.com/doi/full/10.1080/14017431.2019.1590628