Prognostic efficacy of C-reactive protein/albumin ratio in ST elevation myocardial infarction
Yazarlar (8)
Metin Çağdaş
Kafkas Üniversitesi, Türkiye
Süleyman Karakoyun
Prof. Dr. Yavuz KARABAĞ
Kafkas Üniversitesi, Türkiye
Mahmut Yesin
Kafkas Üniversitesi, Türkiye
Öznur Sadioğlu Çağdaş
Halil İbrahim Tanboğa
| Makale Türü | Özgün Makale (SSCI, AHCI, SCI, SCI-Exp dergilerinde yayınlanan tam makale) | ||
| Dergi Adı | Scandinavian Cardiovascular Journal (Q4) | ||
| Dergi ISSN | 1401-7431 Wos Dergi Scopus Dergi | ||
| Dergi Tarandığı Indeksler | SCI-Expanded | ||
| Makale Dili | İngilizce | Basım Tarihi | 04-2019 |
| Cilt / Sayı / Sayfa | 53 / 2 / 83–90 | DOI | 10.1080/14017431.2019.1590628 |
| Makale Linki | https://www.tandfonline.com/doi/full/10.1080/14017431.2019.1590628 | ||
| Özet |
| Although the prognostic efficacy of C-reactive protein (mg/L) and albumin levels (g/L) has been previously associated with poor prognosis in ST elevation myocardial infarction (STEMI), to the best of our knowledge, the prognostic efficacy of C-reactive protein/Albumin ratio (CAR) (mg/g) has not been investigated yet. Thus, this study aimed to investigate the potential efficacy of the CAR in predicting prognosis in STEMI patients. We conducted a detailed investigation of 2437 patients with first STEMI treated with a primary percutaneous coronary intervention. After evaluation regarding to exclusion criteria, 2243 patients were found to be eligible for analysis. The mean follow-up of the study was 34 ± 15 months. The median CAR value of the study population was 2.70 (range: 1.44-4.76), and the patients were divided into three tertiles according to their CAR values. Kaplan-Meier survival analysis showed significantly lower in-hospital and long-term survival rates for the patients in a high CAR tertile. In addition, the CAR was found to be an independent predictor of all-cause mortality (Hazards ratio: 1.033, 95% Confidence Interval: 1.007-1.061, p = .033), and the prognostic performance of the CAR was superior to that of C-reactive protein, albumin, and neutrophil to lymphocyte ratio in the receiver operating characteristic curve comparison. The CAR, a newly introduced inflammation-based risk index, was found to be a potentially useful prognostic tool for predicting a poor prognosis in STEMI patients. However, this finding needs to be validated in the future prospective studies. |
| Anahtar Kelimeler |
| ST elevation myocardial infarction | C-reactive protein to Albumin ratio | all-cause mortality |
BM Sürdürülebilir Kalkınma Amaçları
| Atıf Sayıları |