Association of serum uric acid levels with SYNTAX score II and long term mortality in the patients with stable angina pectoris who undergo percutaneous coronary interventions due to multivessel and/or unprotected left main disease
  
Yazarlar (10)
Prof. Dr. Yavuz KARABAĞ Kafkas Üniversitesi, Türkiye
Prof. Dr. İbrahim RENCÜZOĞULLARI Kafkas Üniversitesi, Türkiye
Metin Çağdaş Kafkas Üniversitesi, Türkiye
Doç. Dr. Eray ATALAY Kafkas Üniversitesi, Türkiye
Öznur Sadioğlu Çağdaş Kafkas Üniversitesi, Türkiye
Mustafa Ozan Gürsoy
Makale Türü Özgün Makale (SSCI, AHCI, SCI, SCI-Exp dergilerinde yayınlanan tam makale)
Dergi Adı The International Journal of Cardiovascular Imaging (Q3)
Dergi ISSN 1569-5794 Wos Dergi Scopus Dergi
Dergi Tarandığı Indeksler SCI
Makale Dili İngilizce Basım Tarihi 01-2019
Cilt / Sayı / Sayfa 35 / 1 / 1–7 DOI 10.1007/s10554-018-1446-6
Makale Linki http://link.springer.com/10.1007/s10554-018-1446-6
Özet
Serum uric acid (SUA) level was shown in various studies to be related to the presence of coronary artery disease and subsequent cardiovascular events. The aim of the present study was to evaluate the association of SUA with SYNTAX score II (SSII) and the long-term prognosis of patients with stable angina pectoris who underwent percutaneous revascularization due to multivessel disease (MVD) and/or unprotected left main disease (UPLMD). Two-hundred and ninety patients with MVD and/or UPLMD who were treated consecutively with percutaneous coronary intervention (PCI) were included in the present study. The study population was divided into high SSII (n: 145; SSII > 32.9) and low SSII (n: 145; SSII ≤ 32.9) according to the median SSII value. The SUA value was significantly higher in the high SSII group than in the low SSII group (5.53 ± 1.95 vs. 6.07 ± 1.88; p = 0.001) and was found to be an independent predictor of high SSII (OR 1.306; 95% CI 1.119-1.525; p = 0,001). Twenty-eight patients (9.7%) died during the long-term follow-up, and SUA and SSII were additionally found to be independent predictors of long-term mortality (HR 1.245, 95% CI 1.046-1.482, p = 0.014; HR 1.042, 95% CI 1.007-1.079, p = 0.018, respectively). In the present study, SUA level was demonstrated to be associated with high SSII and long-term mortality in patients with MVD and/or UPLMD who were treated with PCI.
Anahtar Kelimeler
Serum uric acid | SYNTAX score II | Long-term mortality | Stable angina pectoris | Multivessel disease | Unprotected left main disease | Percutaneous coronary intervention