Fullerene-PAMAM(G5) composite modified impedimetric biosensor to detect Fetuin-A in real blood samples
Yazarlar (6)
Doç. Dr. Zihni Onur UYGUN Kafkas Üniversitesi, Türkiye
Çağdaş Şahin Ege Üniversitesi, Türkiye
Yasemin Akçay Ege Üniversitesi, Türkiye
Ali Akdemir Ege Üniversitesi, Türkiye
Ferhan Girgin Sağın Ege Üniversitesi, Türkiye
| Makale Türü | Özgün Makale (SSCI, AHCI, SCI, SCI-Exp dergilerinde yayınlanan tam makale) | ||
| Dergi Adı | Analytical Biochemistry (Q2) | ||
| Dergi ISSN | 0003-2697 Wos Dergi Scopus Dergi | ||
| Dergi Tarandığı Indeksler | SCI-Expanded | ||
| Makale Dili | İngilizce | Basım Tarihi | 12-2018 |
| Cilt / Sayı / Sayfa | 542 / 1 / – | DOI | 10.1016/j.ab.2017.11.007 |
| Makale Linki | http://dx.doi.org/10.1016/j.ab.2017.11.007 | ||
| Özet |
| The aim of this study is to develop a nanomaterial-dendrimer composite modified biosensor to detect Fetuin-A (HFA) in real blood samples. For this purpose, we designed an Electrochemical Impedance Spectroscopy (EIS) based anti-Fetuin-A (Anti-HFA) modified biosensor system and tested in real blood samples. Chronoimpedance was also employed. The same samples were analyzed with ELISA and the results were compared for validation of the new system. Gold screen printed electrodes (AuSPE) were used as transducer. Firstly, a self-assembly monolayer (SAM) was formed on gold surface by 4-aminothiophenol (4-ATP), Fullerene and PAMAM-NH2 (G5), layers were formed, consecutively. Then Anti-HFA was immobilized on Au/4-ATP/Fullerene/PAMAM electrode via glutaraldehyde. The chronoimpedance test was employed to investigate the optimum analysis duration. According to the data of … |
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BM Sürdürülebilir Kalkınma Amaçları
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| Google Scholar | 39 |