How Did the Updated 2019 European Society of Cardiology/European Atherosclerosis Society Risk Categorization for Patients with Diabetes Affect the Risk Perception and Lipid Goals? A Simulated Analysis of Real-life Data from EPHESUS Study
Yazarlar (29)
Özcan Başaran Muğla Sıtkı Koçman Üniversitesi, Türkiye
Volkan Doğan Muğla Sıtkı Koçman Üniversitesi, Türkiye
Kadir Uğur Mert Eskişehir Osmangazi Üniversitesi, Türkiye
Bülent Özlek Muğla Sıtkı Koçman Üniversitesi, Türkiye
Eda Özlek Muğla Sıtkı Koçman Üniversitesi, Türkiye
Oğuzhan Çelik Muğla Sıtkı Koçman Üniversitesi, Türkiye
Cem Çil Türkiye
İbrahim Halil Özdemir Türkiye
Prof. Dr. İbrahim RENCÜZOĞULLARI Kafkas Üniversitesi, Türkiye
Fatma Özpamuk Karadeniz Karamanoğlu Mehmetbey Üniversitesi, Türkiye
Mehmet Tekinalp T.C. Sağlık Bakanlığı, Türkiye
Lütfü Aşkın Gaziantep İslam Bilim ve Teknoloji Üniversitesi, Türkiye
Selami Demirelli
Sağlık Bilimleri Üniversitesi, Türkiye
Sağlık Bilimleri Üniversitesi, Türkiye
Erkan Gencer
T.C. Sağlık Bakanlığı, Türkiye
T.C. Sağlık Bakanlığı, Türkiye
Lütfü Bekar Hitit Üniversitesi, Türkiye
Müjdat Aktaş Türkiye
Macit Kalçık Hitit Üniversitesi, Türkiye
Gökhan Aksan T.C. Sağlık Bakanlığı, Türkiye
Göksel Çinier
Sağlık Bilimleri Üniversitesi, Türkiye
Sağlık Bilimleri Üniversitesi, Türkiye
Kadriye Halli Akay
Nihat Pekel Türkiye
Gurbet Özge Mert Eskişehir Osmangazi Üniversitesi, Türkiye
Utku Şenol T.C. Sağlık Bakanlığı, Türkiye
Vahit Demir
Türkiye
Türkiye
Sinan İnci Aksaray Üniversitesi, Türkiye
Emir Derviş T.C. Sağlık Bakanlığı, Türkiye
Murat Biteker
Muğla Sitki Koçman Üniversitesi, Türkiye
Muğla Sitki Koçman Üniversitesi, Türkiye
Latife Meral Kayıkçıoğlu Ege Üniversitesi, Türkiye
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Özgün Makale
(SSCI, AHCI, SCI, SCI-Exp dergilerinde yayınlanan tam makale)
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| Dergi Adı | The Anatolian Journal of Cardiology (Q3) | ||
| Dergi ISSN | 2149-2263 Wos Dergi Scopus Dergi | ||
| Dergi Tarandığı Indeksler | SCI-Expanded | ||
| Makale Dili | İngilizce | Basım Tarihi | 02-2023 |
| Cilt / Sayı / Sayfa | 27 / 2 / 78–87 | DOI | 10.14744/AnatolJCardiol.2022.2012 |
| Makale Linki | http://dx.doi.org/10.14744/anatoljcardiol.2022.2012 | ||
| Özet |
| Background: The recent 2019 European Society of Cardiology/European Atherosclerosis Society practice guidelines introduced a new risk categorization for patients with diabetes. We aimed to compare the implications of the 2016 and 2019 European Society of Cardiology/European Atherosclerosis Society guidelines with regard to the lipid-lowering treatment use, low-density lipoprotein cholesterol goal attainment rates, and the estimated proportion of patients who would be at goal in an ideal setting. Methods: Patients with diabetes were classified into 4 risk categories according to 2019 European Society of Cardiology/European Atherosclerosis Society dyslipidemia guidelines from the database of EPHESUS (cross-sectional, observational, countrywide registry of cardiology outpatient clinics) study. The use of lipid-lowering treatment and low-density lipoprotein cholesterol goal attainment rates were then compared according to previous and new guidelines. Results: This analysis included a total of 873 diabetic adults. Half of the study population (53.8%) were on lipid-lowering treatment and almost one-fifth (19.1%) were on highintensity statins. While low-density lipoprotein cholesterol goal was achieved in 19.5% and 7.5% of patients, 87.4% and 69.6% would be on target if their lipid-lowering treatment was intensified according to 2016 and 2019 European Society of Cardiology/European Atherosclerosis Society lipid guidelines, respectively. The new target <55 mg/dL could only be achieved in 2.2% and 8.1% of very high-risk primary prevention and secondary prevention patients, respectively. Conclusion: The control of dyslipidemia was extremely poor among patients with diabetes. The use of lipid-lowering treatment was not at the desired level, and high-intensity lipid-lowering treatment use was even lower. Our simulation model showed that the highdose statin plus ezetimibe therapy would improve goal attainment; however, it would not be possible to get goals with this treatment in more than one-third of the patients. |
| Anahtar Kelimeler |
BM Sürdürülebilir Kalkınma Amaçları
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| TRDizin | 1 |