Synthesis, Spectroscopic Analysis, Biological Evaluation, and In Silico Studies of Novel Benzenesulfonate-Derived Schiff-Mannich Bases
Yazarlar (6)
Dr. Öğr. Üyesi Ahmet HARMANKAYA Kafkas Üniversitesi, Türkiye
Doç. Dr. Namık Kılınç Iğdır Üniversitesi, Türkiye
Doç. Dr. Murat BEYTUR Kafkas Üniversitesi, Türkiye
Yonca Yılmaz
Kafkas Üniversitesi, Türkiye
Kafkas Üniversitesi, Türkiye
Doç. Dr. Sevda MANAP Kafkas Üniversitesi, Türkiye
Prof. Dr. Haydar YÜKSEK Kafkas Üniversitesi, Türkiye
| Makale Türü |
Özgün Makale
(SSCI, AHCI, SCI, SCI-Exp dergilerinde yayınlanan tam makale)
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| Dergi Adı | Journal of the Chemical Society of Pakistan (Q4) | ||
| Dergi ISSN | 0253-5106 Wos Dergi Scopus Dergi | ||
| Dergi Tarandığı Indeksler | SCI-Expanded | ||
| Makale Dili | Türkçe | Basım Tarihi | 01-2023 |
| Cilt / Sayı / Sayfa | 45 / 4 / 323–335 | DOI | 10.52568/001280/JCSP/45.04.2023 |
| Makale Linki | http://dx.doi.org/10.52568/001280/jcsp/45.04.2023 | ||
| UAK Araştırma Alanları |
Organik Kimya
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| Özet |
| In the current study, 3-formyl phenyl benzenesulfonate is created by reacting 3-hydroxybenzaldehyde with benzene sulfonyl chloride, which is aided by triethylamine. Nine unique (Z)-3-[(3-substituted-5-oxo-1, 5-dihydro-4H-1, 2, 4-triazol-4-yl)-iminomethyl] compounds were formed through the reaction of a manufactured 3-formyl phenyl benzenesulfonate chemical with nine 3-alkyl (aryl)-4-amino-4, 5-dihydro-1H-1, 2, 4-triazol-5-one, as detailed in the existing literature. Phenyl benzene sulfonate (S) compounds were purchased. Through the reaction of the Schiff bases that were made a secondary amine, such as morpholine with formaldehyde, heterocyclic Mannich bases of a unique kind were created. Five recently found (Z)-3-[(3-substituted-5-oxo-1, 5-dihydro-4H-1, 2, 4-triazol-4-yl)-iminomethyl] compounds are presented in this work. By reacting phenyl benzene sulfonate (S) with morpholine in the presence of … |
| Anahtar Kelimeler |
| 1,2,4-Triazole ring | Benzenesulfonate | Docking Study | Inhibitory activity | Mannich Bases | Schiff base |
BM Sürdürülebilir Kalkınma Amaçları
| Atıf Sayıları | |
| Scopus | 2 |
| Google Scholar | 2 |