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Assessing mental health in children and adolescent with MTHFR polymorphisms: psychiatric disorders, executive functioning, and symptom profile in a Turkish clinical sample      
Yazarlar
Onur Tuğçe Poyraz Fındık
Türkiye
Funda Gümüştaş
Türkiye
Ayşe Arman
Türkiye
Doç. Dr. Işıl ÖZER
Türkiye
Özet
This study investigated behavioral phenotype, executive functions profile, and the existence of comorbid psychiatric disorders in children and adolescents with methylenetetrahydrofolate reductase (MTHFR) polymorphisms admitted to pediatric metabolism outpatient clinic. Internalizing problems, especially somatic complaints were common in patients with MTHFR. More than half of the cases had emotional control and initiating problems as executive function deficits. Attention-deficit/hyperactivity disorder was the most common psychiatric diagnosis, followed by anxiety disorder. Current findings emphasize that health care providers should be aware of the mental health needs of cases with MTHFR polymorphism in order to make plans of integrative physical and mental health care.
Anahtar Kelimeler
attention-deficit hyperactivity disorder | executive function | genetics | mental health | Methylenetetrahydrofolate reductase (NADPH2)
Makale Türü Özgün Makale
Makale Alt Türü SSCI, AHCI, SCI, SCI-Exp dergilerinde yayımlanan tam makale
Dergi Adı Children's Health Care
Dergi ISSN 0273-9615
Dergi Tarandığı Indeksler SCI-Expanded
Dergi Grubu Q4
Makale Dili İngilizce
Basım Tarihi 01-2021
Doi Numarası 10.1080/02739615.2021.1871616
Makale Linki http://dx.doi.org/10.1080/02739615.2021.1871616