Assessing mental health in children and adolescent with MTHFR polymorphisms: psychiatric disorders, executive functioning, and symptom profile in a Turkish clinical sample
Yazarlar (5)
Doç. Dr. Onur Tuğçe Poyraz Fındık Marmara Üniversitesi Tip Fakültesi, Türkiye
Duygu Murat
Specialty Healthcare, Türkiye
Specialty Healthcare, Türkiye
Prof. Dr. Funda Gümüştaş Marmara Üniversitesi Tip Fakültesi, Türkiye
Ayşe Rodopman Arman
Marmara Üniversitesi Tip Fakültesi, Türkiye
Marmara Üniversitesi Tip Fakültesi, Türkiye
Prof. Dr. Işıl ÖZER Ondokuz Mayis University, Medical School, Türkiye
| Makale Türü | Özgün Makale (SSCI, AHCI, SCI, SCI-Exp dergilerinde yayınlanan tam makale) | ||
| Dergi Adı | Children S Health Care (Q4) | ||
| Dergi ISSN | 0273-9615 Dergi Bilgileri (2021) | ||
| Dergi Tarandığı Indeksler | SCI-Expanded | ||
| Makale Dili | İngilizce | Basım Tarihi | 01-2021 |
| Cilt / Sayı / Sayfa | 50 / 2 / 220–237 | DOI | 10.1080/02739615.2021.1871616 |
| Makale Linki | http://dx.doi.org/10.1080/02739615.2021.1871616 | ||
| UAK Araştırma Alanları |
Çocuk Metabolizma Hastalıkları (Çocuk Sağlığı ve Hastalıkları)
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| Özet |
| This study investigated behavioral phenotype, executive functions profile, and the existence of comorbid psychiatric disorders in children and adolescents with methylenetetrahydrofolate reductase (MTHFR) polymorphisms admitted to pediatric metabolism outpatient clinic. Internalizing problems, especially somatic complaints were common in patients with MTHFR. More than half of the cases had emotional control and initiating problems as executive function deficits. Attention-deficit/hyperactivity disorder was the most common psychiatric diagnosis, followed by anxiety disorder. Current findings emphasize that health care providers should be aware of the mental health needs of cases with MTHFR polymorphism in order to make plans of integrative physical and mental health care. |
| Anahtar Kelimeler |
| attention-deficit hyperactivity disorder | executive function | genetics | mental health | Methylenetetrahydrofolate reductase (NADPH2) |
BM Sürdürülebilir Kalkınma Amaçları
| Atıf Sayıları |