| Yazarlar |
Dr. Öğr. Üyesi Buket BOĞA KURU
Kafkas Üniversitesi, Türkiye |
Doç. Dr. Mustafa MAKAV
Kafkas Üniversitesi, Türkiye |
Arş. Gör. Gülden YILDIZ
Türkiye |
Doç. Dr. Mükremin ÖLMEZ
Kafkas Üniversitesi, Türkiye |
Doç. Dr. Mushap KURU
Kafkas Üniversitesi, Türkiye |
Dr. Öğr. Üyesi Fikret BEKTAŞOĞLU
Kafkas Üniversitesi, Türkiye |
Hatice Beşeren
|
Prof. Dr. Tarkan ŞAHİN
Kafkas Üniversitesi, Türkiye |
Prof. Dr. Turgut KIRMIZIBAYRAK
Kafkas Üniversitesi, Türkiye |
| Özet |
| The goal of this study was to investigate the effects of Ferula communis L. on growth performance, relative organ weights, tissue and serum oxidative status, and biochemical and histopathological changes in rats exposed to continuous light. Rats exposed to continuous light for 10 days were given F. communis orally. Daily body weight was recorded, and rats were euthanized by cervical dislocation. Blood was collected to determine relative organ weights, followed by immediate biochemical and histopathological analysis of the organs. Serum and tissue oxidative status were measured. Continuous light exposure in rats resulted in weight loss, decreased ovary, uterus, and kidney weights, diminished total antioxidant status (TAS) along with increased cortisol, total oxidant status, and oxidative stress index. However, F. communis treatment reduced serum cortisol concentration and alleviated oxidative stress by increasing TAS even under prolonged light exposure conditions. Neither continuous light exposure nor F. communis treatment caused significant changes in malondialdehyde and glutathione in organ tissues. Although continuous light caused an increase in the number of cystic follicles, F. communis treatment did not seem to have a positive effect on cystic follicle formation. In conclusion, continuous light exposure stressed the rats and increased cortisol, as well as stimulated oxidative stress and cystic follicle formation. F. communis treatment can help alleviate the harmful effects of constant light exposure. |
| Anahtar Kelimeler |
| Body weight | Continuous light stress | Cortisol | Cystic follicle | Ferula | Ovary | Oxidative stress |
| Makale Türü | Özgün Makale |
| Makale Alt Türü | SSCI, AHCI, SCI, SCI-Exp dergilerinde yayımlanan tam makale |
| Dergi Adı | Kafkas Universitesi Veteriner Fakultesi Dergisi |
| Dergi ISSN | 1300-6045 |
| Dergi Tarandığı Indeksler | SCI-Expanded |
| Dergi Grubu | Q3 |
| Makale Dili | İngilizce |
| Basım Tarihi | 04-2024 |
| Cilt No | 30 |
| Sayı | 3 |
| Sayfalar | 363 / 374 |
| Doi Numarası | 10.9775/kvfd.2023.31403 |
| Makale Linki | https://vetdergikafkas.org/content.php?id=219 |
| Atıf Sayıları | |
| Google Scholar | 1 |
