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Benefits of Some Phytochemical Compounds in Experimental Sepsis Models: A Therapeutic Perspective   
Yazarlar (3)
Bengül Özdemir
Kafkas Üniversitesi, Türkiye
Doç. Dr. Pınar BAYRAM Doç. Dr. Pınar BAYRAM
Kafkas Üniversitesi, Türkiye
Prof. Dr. Selina AKSAK KARAMEŞE Prof. Dr. Selina AKSAK KARAMEŞE
Kafkas Üniversitesi, Türkiye
Devamını Göster
Özet
Sepsis represents a major contributor to mortality among critically ill patients, imposing a substantial eco- nomic strain on health-care systems. The uncontrolled inflammatory response during sepsis development, often leading to multiorgan failure and death, remains a challenge despite advances in antibiotics and sup- portive care. Factors such as antibiotic resistance, noninfectious causes, and delays in treatment initiation con- tribute to the complexity of managing sepsis. This review explores alternative treatment strategies focusing on the ameliorative effects of widely consumed phytochemicals and their cellular and molecular mechanisms in various in vitro and in vivo sepsis models. Preemptive administration of phytochemicals before sepsis onset appears effective, emphasizing their potential as adjunct or complementary therapeutic agents for critically ill sepsis patients. As a consequence, phytochemicals can be included in treatment regimens to enhance overall effectiveness and expedite the healing process.
Anahtar Kelimeler
Makale Türü Diğer (Teknik, not, yorum, vaka takdimi, editöre mektup, özet, kitap krıtiği, araştırma notu, bilirkişi raporu ve benzeri)
Makale Alt Türü ESCI dergilerinde yayımlanan teknik not, editöre mektup, tartışma, vaka takdimi ve özet türünden makale
Dergi Adı The Eurasian Journal of Medicine
Dergi ISSN 1308-8742 Wos Dergi Scopus Dergi
Dergi Tarandığı Indeksler Scopus
Makale Dili İngilizce
Basım Tarihi 12-2023
Cilt No 55
Doi Numarası 10.5152/eurasianjmed.2023.23382
Makale Linki http://dx.doi.org/10.5152/eurasianjmed.2023.23382