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Effect of sainfoin (Onobrychis viciifolia Scop.) seed‐based diet on rats: A comprehensive evaluation of hemogram, biochemistry, and histopathology        
Yazarlar (10)
Evan B. Craine
Doç. Dr. Mustafa MAKAV Doç. Dr. Mustafa MAKAV
Türkiye
Prof. Dr. Serpil DAĞ Prof. Dr. Serpil DAĞ
Türkiye
Arş. Gör. Ayfer YILDIZ UYSAL Arş. Gör. Ayfer YILDIZ UYSAL
Türkiye
Hüseyin Avni Eroğlu
Çanakkale Onsekiz Mart Üniversitesi, Türkiye
Dr. Öğr. Üyesi Buket BOĞA KURU Dr. Öğr. Üyesi Buket BOĞA KURU
Türkiye
Dr. Öğr. Üyesi Fikret BEKTAŞOĞLU Dr. Öğr. Üyesi Fikret BEKTAŞOĞLU
Türkiye
Spencer Barriball
Brandon Schlautman
Muhammet Şakiroğlu
Türkiye
Devamını Göster
Özet
Sainfoin species ( spp.) have been employed for centuries as an essential forage for ruminant animals, both for grazing and as hay. The seeds produced by sainfoin have also been investigated as an animal feed source and were indicated to be a particularly protein-rich supplement for monogastric animals. This study explores the effects of two sainfoin seed inclusion rates in rat diets compared to a control diet, focusing on blood biochemical parameters and a comprehensive histopathological evaluation of multiple organ systems. Thus, we provide a novel contribution to the body of evidence investigating sainfoin seeds as a protein supplement in monogastric animal diets. In this 21-day experiment, seven rats each were assigned to the control group, a 5% sainfoin seed group, and a 10% sainfoin seed group. The control group received standard feed and water; the second group received feed with 5% sainfoin seeds; and the third group received feed with 10% sainfoin seeds. At the experiment's end, necropsies and evaluations were conducted. Histopathological exams revealed normal organ structures in all 21 samples, regardless of the group. Blood analysis showed statistically significant decreases in creatine, ALT, P, Ca, and Mg levels in the sainfoin seed groups compared to the control group, with most values nearing reference levels, suggesting potential benefits. Notably, no adverse effects were observed when sainfoin seeds were included at 5% and 10% in the rat feed. These findings contribute to a growing body of research investigating the inclusion of sainfoin seeds in monogastric animal diets, which is a foundational component of assessing sainfoin's potential as a novel pulse crop for human consumption.
Anahtar Kelimeler
blood parameters | histopathology | Perennial Baki (TM) bean | rats | sainfoin seed
Makale Türü Özgün Makale
Makale Alt Türü SSCI, AHCI, SCI, SCI-Exp dergilerinde yayımlanan tam makale
Dergi Adı Food Science & Nutrition
Dergi ISSN 2048-7177 Wos Dergi Scopus Dergi
Dergi Tarandığı Indeksler SCI-Expanded
Dergi Grubu Q2
Makale Dili İngilizce
Basım Tarihi 06-2024
Cilt No 12
Sayı 7
Sayfalar 4692 / 4701
Doi Numarası 10.1002/fsn3.4117
Makale Linki http://dx.doi.org/10.1002/fsn3.4117