The utility of Hibiscus sabdariffa L. to prepare metal oxides NPs for clinical application on osteoporosis supported by theoretical study
Yazarlar (5)
Zahraa S. Al-Garawi
Mustansiriyah University, Irak
Mustansiriyah University, Irak
Ahmad H. Ismail Al-Qaisi
Mustansiriyah University, Irak
Mustansiriyah University, Irak
Kawthar Amer Al-Shamari
Mustansiriyah University, Irak
Mustansiriyah University, Irak
Doç. Dr. Füreya Elif ÖZTÜRKKAN Kafkas Üniversitesi, Türkiye
Prof. Dr. Hacali NECEFOĞLU Kafkas Üniversitesi, Türkiye
| Makale Türü | Özgün Makale (SSCI, AHCI, SCI, SCI-Exp dergilerinde yayınlanan tam makale) | ||
| Dergi Adı | Bioprocess and Biosystems Engineering (Q2) | ||
| Dergi ISSN | 1615-7591 Dergi Bilgileri (2024) | ||
| Dergi Tarandığı Indeksler | SCI-Expanded | ||
| Makale Dili | Türkçe | Basım Tarihi | 04-2024 |
| Cilt / Sayı / Sayfa | 47 / 5 / 753–766 | DOI | 10.1007/s00449-024-03012-5 |
| Makale Linki | http://dx.doi.org/10.1007/s00449-024-03012-5 | ||
| UAK Araştırma Alanları |
Anorganik Kimya
Spektroskopi
|
||
| Özet |
| Green synthesis of metal oxides as a treatment for bone diseases is still exploring. Herein, MgO and Fe2O3 NPs were prepared from the extract of Hibiscus sabdariffa L. to study their effect on vit D3, Ca+2, and alkaline phosphatase enzyme ALP associated with osteoporosis. Computational chemistry was utilized to gain insight into the possible interactions. These oxides were characterized by X-ray diffraction, SEM, FTIR, and AFM. Results revealed that green synthesis of MgO and Fe2O3 NPs was successful with abundant. MgO NPs were in vitro applied on osteoporosis patients (n = 35) and showed a significant elevation of vit D3 and Ca+2 (0.0001 > p < 0.001) levels, compared to healthy volunteers (n = 25). Thus, Hibiscus sabdariffa L. is a good candidate to prepare MgO NPs, with a promising enhancing effect on vit D3 and Ca+2 in osteoporosis. In addition, interactions of Fe2O3 and MgO NPs with ALP were … |
| Anahtar Kelimeler |
| Fe2O3 NPs | Green synthesis | Hibiscus sabdariffaL | MgO NPs | Molecular docking | Osteoporosis |
BM Sürdürülebilir Kalkınma Amaçları
| Atıf Sayıları | |
| Web of Science | 4 |
| Scopus | 3 |
| Google Scholar | 3 |