Yazarlar |
Doç. Dr. Timor OMAR
Türkiye |
Metin Çağdaş
Türkiye |
Dr. Öğr. Üyesi İnanç ARTAÇ
Kafkas Üniversitesi, Türkiye |
Dr. Öğr. Üyesi Muammer KARAKAYALI
Kafkas Üniversitesi, Türkiye |
Dr. Öğr. Üyesi Doğan İLİŞ
Kafkas Üniversitesi, Türkiye |
Dr. Öğr. Üyesi Ayça ARSLAN
Kafkas Üniversitesi, Türkiye |
Doç. Dr. Yavuz KARABAĞ
Kafkas Üniversitesi, Türkiye |
Mahmut Yesin
Türkiye |
Mustafa Avcı
Türkiye |
Prof. Dr. İbrahim RENCÜZOĞULLARI
Kafkas Üniversitesi, Türkiye |
Özet |
Objective: We investigated the relationship between anemia and cardiac functions by conventional and speckle-tracking echocardiography (STE) in patients with end-stage renal disease (ESRD) receiving hemodialysis. Methods: One hundred six patients with ESRD receiving hemodialysis were included in this cross-sectional study. The conventional echocardiography and STE findings were compared between the patients with and without anemia. In addition, a comparison of the findings between the ESRD patients and healthy controls consisting of 68 participants was conducted. Results: Compared to healthy controls, ESRD patients had lower left ventricular ejection fraction (LVEF), left ventricular global longitudinal strain (LVGLS), and left atrial reservoir strain (LASr) [53% (48-57) vs. 65% (62-68), -15.2 (-16.9˗ -13.6) vs. -19.7 (-16.9˗ -13.6), and -21.9 (-29.5˗ -15.3) vs. -29.9 (-35.3˗ -22.8), respectively, P-value <0.001 for all]. Of the ESRD patients, 70 (66%) had anemia. ESRD patients with anemia had higher interventricular septum (IVS), posterior wall (PW), and left atrial volume index (LAVi) values than patients without anemia. In addition, ESRD patients with anemia had lower LVEF, LVGLS, and LASr than patients without anemia [median (IQR), 13 (12-15) vs. 12 (11-14), P=0.004, 13 (12-15) vs. 12 (11-13.5), P<0.005, 43 (35-55) vs. 34.7 (28-50), P=0.013, 52 (48-55) vs. 56 (47.5-60), P=0.016, -14.6 (-16.4˗ -13.5) vs. -16 (-18.6˗ -14.7), P=0.003, and -21.6 (-30.5˗ -16.3) vs. -30.5 (-33.6˗ -23.3), P=0.006, respectively]. In multivariable logistic regression analysis, diabetes, PW, LASr, and LVGLS were independently associated with the presence of anemia in ESRD patients. Conclusion: Our study confirmed impaired cardiac mechanics in ESRD hemodialysis patients and showed that anemia was associated with further worsening cardiac mechanics in this population. |
Anahtar Kelimeler |
Makale Türü | Özgün Makale |
Makale Alt Türü | Ulusal alan endekslerinde (TR Dizin, ULAKBİM) yayımlanan tam makale |
Dergi Adı | The European Research Journal |
Dergi ISSN | 2149-3189 |
Dergi Tarandığı Indeksler | TR DİZİN |
Makale Dili | Türkçe |
Basım Tarihi | 01-2024 |
Cilt No | 10 |
Sayı | 1 |
Sayfalar | 118 / 126 |
Doi Numarası | 10.18621/eurj.1401607 |
Makale Linki | http://dx.doi.org/10.18621/eurj.1401607 |