| Yazarlar |
Şerif Hamideyin
Türkiye |
Dr. Öğr. Üyesi İnanç ARTAÇ
Kafkas Üniversitesi, Türkiye |
| Özet |
| Background: In this study, we sought to examine the statistical association of plasma osmolarity with no- reflow development in patients with ST-segment elevation myocardial infarction (STEMI) who were treated with primary percutaneous coronary intervention (pPCI). Methods: In this retrospective study, we included data from 1294 consecutive STEMI patients who have undergone pPCI. For each patient, we measured the plasma osmolarity using the following equation: 2 × sodium + 0.9 glucose + 0.93 × urea × 0.5. Results: Occurrence of angiographic no-reflow was 21.7% (n = 281) in the study. The mean plasma osmolar- ity level was significantly higher in patients with no-reflow compared to those without no-reflow (300.6 ± 9.4 mOsmol/L versus 292.8 ± 10.5 mOsmol/L, P < .001, respectively). In multivariate logistic regression analysis, plasma osmolarity was found to be independently related to no-reflow development (odds ratio: 1.061; 95% CI, 1.045-1.076; P < .001). According to the receiver operating characteristic curve analysis, a plasma osmo- larity level greater than 290.2 mOsmol/L was identified as the optimal value for predicting the occurrence of no-reflow. This cutoff demonstrated a sensitivity of 91.8% and a specificity of 45.8%. Conclusion: This is the first study to establish an independent relationship between higher plasma osmolarity and the development of no-reflow in patients with STEMI who have undergone pPCI. This finding suggests that plasma osmolarity may be a useful marker for the prediction of no-reflow in STEMI patients who have undergone pPCI. |
| Anahtar Kelimeler |
| Makale Türü | Özgün Makale |
| Makale Alt Türü | ESCI dergilerinde yayımlanan tam makale |
| Dergi Adı | The Eurasian Journal of Medicine |
| Dergi ISSN | 1308-8742 |
| Dergi Tarandığı Indeksler | ESCI |
| Makale Dili | İngilizce |
| Basım Tarihi | 02-2024 |
| Cilt No | 56 |
| Sayı | 1 |
| Sayfalar | 27 / 34 |
| Doi Numarası | 10.5152/eurasianjmed.2024.23143 |
| Makale Linki | http://dx.doi.org/10.5152/eurasianjmed.2024.23143 |
| Atıf Sayıları |
