Seroprevalence rates of Toxoplasma gondii, Rubella, Cytomegalovirus among first trimester pregnant women in Istanbul
Yazarlar (8)
Doç. Dr. Ayşegül Özel İstanbul Üniversitesi-Cerrahpaşa, Türkiye
Müjde Canday
Kafkas Üniversitesi, Türkiye
Doç. Dr. Aslıhan YURTKAL Kafkas Üniversitesi, Türkiye
Prof. Dr. Ebru Alıcı Davutoğlu İstanbul Üniversitesi-Cerrahpaşa, Türkiye
Yaşam Kemal Akpak
Türkiye
Alper İleri
Türkiye
Adnan Budak
Türkiye
Prof. Dr. Rıza Madazlı İstanbul Üniversitesi-Cerrahpaşa, Türkiye
Makale Türü Açık Erişim Özgün Makale (Diğer hakemli uluslarası dergilerde yayınlanan tam makale)
Dergi Adı International Journal of Reproduction, Contraception, Obstetrics and Gynecology
Dergi ISSN 2320-1770
Dergi Tarandığı Indeksler Copernicus
Makale Dili İngilizce Basım Tarihi 01-2021
Kabul Tarihi – Yayınlanma Tarihi 26-12-2020
Cilt / Sayı / Sayfa 10 / 1 / 22–25 DOI 10.18203/2320-1770.ijrcog20205749
Makale Linki http://dx.doi.org/10.18203/2320-1770.ijrcog20205749
UAK Araştırma Alanları
Kadın Hastalıkları ve Doğum
Özet
Background: Toxoplasma Gondii, Rubella, and Cytomegalovirus (CMV) are the most common causes of congenital infections worldwide. There is not a consensus on these infectious agents should be screened during pregnancy. The aim of this study is to determine the prevalence of toxoplasma, rubella, and CMV infections in order to know the need for antenatal screening.Methods: This retrospective cross-sectional study was performed on 1309 ambulatory pregnant patients who applied to the obstetric clinic of a university hospital between October 2016 and April 2018. Documents of patients in the first trimester were reviewed and serologic data of Toxoplasma gondii, CMV, Rubella infections were retrieved from the computer database.Results: Of 1309 pregnant women, positivity for anti-Toxoplasma IgG antibody was 352(26.9%), while 17(1.3%) of the subjects tested were positive for the anti-Toxoplasma IgM antibody. These positivities of the pregnant women for anti-Rubella IgG and IgM were 1147(87.6%) and (0.1%), respectively. These positivities of the pregnant women for anti-CMV IgG and IgM were 1163(88.8%) and 17(1.3%), respectively.Conclusions: We detected high rates of immunity against Rubella and CMV but low rates of immunity against Toxoplasma in this retrospective cohort of pregnant women. Due to high rates of seropositivity against Rubella and CMV, routine nationwide screening may not be necessary.
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