| Yazarlar (5) |
Ümit Yaşar
Türkiye |
|
Cemalettin Ayvazoğlu
Türkiye |
|
Zehra Gül Yaşar
Türkiye |
|
Şemistan Kızıltepe
Türkiye |
Dr. Öğr. Üyesi Nilgün AYDIN
Kafkas Üniversitesi, Türkiye |
| Özet |
| The most common etiologic agent that causes canine hepatozoonosis is Hepatozoon canis (H. canis). High parasitemia is associated with symptoms of fever, anorexia, weight loss, anaemia, ocular discharge, and paralysis of the hind legs. The agent has also been reported to cause myocardial lesions. Troponins are considered the gold standard as they have high sensitivity and specificity for myocardial injury. The study consisted of a total of 27 dogs brought to Iğdır University Animal Hospital, 15 dogs diagnosed with H. canis infection by polymerase chain reaction analysis, and 12 healthy dogs. Of the examined dogs, 59.3 % were female, and 40.7 % were male. Of the dogs, 55.6 % were 4 years old and under, and 44.4 % were 5 years old and over. This study determined high-sensitivity cardiac troponin I (hs-cTnI) and T (hs-cTnT) levels in healthy dogs as 0.1262 and 0.1054 ng mL-1, respectively. In dogs infected with H. canis, hs-cTnI and hs-cTnT levels were 0.4706 and 0.3056 ng mL-1, respectively. In addition, there was a significant difference in serum Alanine aminotransferase (ALT), aspartate aminotransferase (AST), alkaline phosphatase (ALP), lactate dehydrogenase (LDH), and albumin levels in dogs infected with H.canis compared to the control. There was no significant increase in cholesterol and calcium levels. In conclusion, there was a significantly higher increase in hs-cTnT and hs-cTnI levels in dogs infected with H. canis. Considering that even the slightest change in troponin levels is important for prognosis, H. canis may have caused myocardial injury in dogs in our study. Besides, the relative increase in hs-cTnT and hs-cTnI detected in the healthy animal group may indicate various possible causes, such as low clearance and distant myocardial ischaemic events. |
| Anahtar Kelimeler |
| Makale Türü | Özgün Makale |
| Makale Alt Türü | Ulusal alan endekslerinde (TR Dizin, ULAKBİM) yayımlanan tam makale |
| Dergi Adı | ISPEC Journal of Agricultural Sciences |
| Dergi ISSN | 2717-7238 |
| Dergi Tarandığı Indeksler | TR DİZİN |
| Makale Dili | Türkçe |
| Basım Tarihi | 01-2024 |
| Doi Numarası | 10.5281/zenodo.11336681 |
| Makale Linki | https://www.ispecjournal.com/index.php/ispecjas/article/view/590 |
| Atıf Sayıları |
