Can Polyphenols be Used as Anti-Inflammatory Agents against Covid-19 (SARS-CoV-2)-Induced Inflammation?

GELEN, VOLKAN; KÜKÜRT, ABDULSAMED; Şengül, Emin; BAŞER, ÖMER FARUK; KARAPEHLİVAN, MAHMUT

doi:10.5772/intechopen.98684

Can Polyphenols be Used as Anti-Inflammatory Agents against Covid-19 (SARS-CoV-2)-Induced Inflammation? (Phenolic Compounds - Chemistry, Synthesis, Diversity, Non-Conventional Industrial, Pharmaceutical and Therapeutic Applications)

Yazarlar (5)

Doç. Dr. Volkan GELEN Kafkas Üniversitesi, Türkiye

Dr. Öğr. Üyesi Abdulsamed KÜKÜRT Kafkas Üniversitesi, Türkiye

Emin Şengül Türkiye

Dr. Öğr. Üyesi Ömer Faruk BAŞER Kafkas Üniversitesi, Türkiye

Prof. Dr. Mahmut KARAPEHLİVAN Kafkas Üniversitesi, Türkiye

Bölüm Adı	Can Polyphenols be Used as Anti-Inflammatory Agents against Covid-19 (SARS-CoV-2)-Induced Inflammation?
Kitap Adı	Phenolic Compounds - Chemistry, Synthesis, Diversity, Non-Conventional Industrial, Pharmaceutical and Therapeutic Applications
Bölüm Sayfaları	341-361
Kitap Türü	Kitap Bölümü
Kitap Alt Türü	Alanında uluslararası yayınlanan kitap bölümü
Kitap Niteliği	Diğer uluslararası bilimsel kitap
Kitap Dili	İngilizce	Basım Tarihi	01-2021
DOI Numarası	10.5772/intechopen.98684	ISBN	978-1-83969-347-2
Basıldığı Ülke		Basıldığı Şehir
Kitap Linki	https://www.intechopen.com/chapters/77746

Özet

Covid-19 is the causative agent of a beta coronavirus that causes severe inflammatory pneumonia, so excessive inflammation is considered a risk factor for the disease. In Covid-19 disease, an inflammatory response develops in the body. It has been reported as a result of various studies that this response causes damage to various organs and tissues, especially the lungs. According to reports, cytokine storms are largely responsible for death in such patients. Some of the consequences of severe inflammation and cytokine storms include acute respiratory distress syndrome, acute lung injury, and multiple organ dysfunction syndromes. Many studies are showing that there may be various agents to prevent or treat these effects of Covid-19 disease. Some of these agents are phenolic compounds. Phenolic compounds are the most abundant substances in vegetables and fruits. Inflammasomes, their function. It has been stated that phenolic compounds inhibit inflammation by inhibiting cytosolic multiprotein complexes that assemble in response to cytosolic pathogen-associated molecular patterns (PAMPs), and damage-associated molecular patterns (DAMPs) to form active forms of IL-1β and IL-18. It suggested that Apigenin, Resveratrol, Morin, and Silymarin an anti-inflammatory, antioxidant, anti-viral, and anti-microbial compound could be a potential therapeutic agent for severe inflammation from Covid-19.

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Can Polyphenols be Used as Anti-Inflammatory Agents against Covid-19 (SARS-CoV-2)-Induced Inflammation?

Can Polyphenols be Used as Anti-Inflammatory Agents against Covid-19 (SARS-CoV-2)-Induced Inflammation? (Phenolic Compounds - Chemistry, Synthesis, Diversity, Non-Conventional Industrial, Pharmaceutical and Therapeutic Applications)

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