| Yazarlar (2) |
Dr. Öğr. Üyesi Buket BOĞA KURU
Kafkas Üniversitesi, Türkiye |
Doç. Dr. Mustafa MAKAV
Kafkas Üniversitesi, Türkiye |
| Özet |
| This study aims to assess the effects of continuous light stress on the growth performance, live weight gain, specific organ weights, serum melatonin concentration, and modulation of thiol-disulfide homeostasis in rats. The control group (G1, n = 7) with 12-hour light/12-hour dark and the experimental group (G2, n = 7) with 12-hour light/12-hour light were treated for 12 days. Both groups were weighed daily throughout the study. At the end of the experiment, rats were euthanized after being anesthetized. Blood and organ samples were then collected. Continuous light stress decelerated live weight gain from the 4th day with a pronounced effect observed from the 10th day onwards. Serum melatonin concentration decreased with continuous light exposure with a more significant reduction in G2 group. Analysis of alterations in thiol-disulfide homeostasis revealed a decrease in native thiol and total thiol levels and an increase in disulfide levels in rats exposed to continuous light stress. Additionally, the disulfide/native thiol ratio and disulfide/total thiol ratio increased, while the native thiol/total thiol ratio decreased. A robust and positive correlation was observed between melatonin concentration, body weight, and native thiol (r = 0.71, p = 0.005). These findings highlight the effects of continuous light exposure on the metabolic balance, circadian rhythms, and cellular redox balance in biological systems. |
| Anahtar Kelimeler |
| antioxidant | circadian rhythm | light stress | melatonin | thiol-disulfide homeostasis | weight gain |
| Makale Türü | Özgün Makale |
| Makale Alt Türü | SSCI, AHCI, SCI, SCI-Exp dergilerinde yayımlanan tam makale |
| Dergi Adı | ScienceAsia |
| Dergi ISSN | 1513-1874 Wos Dergi Scopus Dergi |
| Dergi Tarandığı Indeksler | SCI-Expanded |
| Dergi Grubu | Q3 |
| Makale Dili | İngilizce |
| Basım Tarihi | 12-2024 |
| Cilt No | 50 |
| Sayı | 6 |
| Sayfalar | 1 / 6 |
| Doi Numarası | 10.2306/scienceasia1513-1874.2024.113 |
| Makale Linki | https://doi.org/10.2306/scienceasia1513-1874.2024.113 |
| Atıf Sayıları |
