| Yazarlar (11) |
Dr. Öğr. Üyesi Elif ÇELİK
Kafkas Üniversitesi, Türkiye |
Doç. Dr. Aliye GÜLMEZ SAĞLAM
Kafkas Üniversitesi, Türkiye |
Prof. Dr. Fatih BÜYÜK
Kafkas Üniversitesi, Türkiye |
Prof. Dr. Salih OTLU
Kafkas Üniversitesi, Türkiye |
Prof. Dr. Mitat ŞAHİN
Kafkas Üniversitesi, Türkiye |
Prof. Dr. Özgür ÇELEBİ
Kafkas Üniversitesi, Türkiye |
Dr. Öğr. Üyesi Mustafa Reha COŞKUN
Kafkas Üniversitesi, Türkiye |
Arş. Gör. Seda GÖKDEMİR
Kafkas Üniversitesi, Türkiye |
Yaren Ersoy
Kafkas Üniversitesi, Türkiye |
Arş. Gör. Eray BÜYÜK
Kafkas Üniversitesi, Türkiye |
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Bengisu Erşahin
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| Özet |
| In this retrospective study, it was evaluated the antimicrobial susceptibility profiles of Bacillus anthracis isolates obtained from human, various samples (blood, spleen, lung, liver, meat) of dead animals (cattle, sheep, dog, horse) that died from anthrax and soil samples from the animal burial areas between 2012 and 2023 from Kars province of Türkiye. In this context, a total of 87 B. anthracis isolates obtained from 1 human, two horses, 51 cattle, 7 sheep, 1 dog, and 25 soil were investigated. The isolates were confirmed as B. anthracis using protective antigen (PA) and capsule (Cap) gen specific PCRs. The Kirby-Bauer disk diffusion method was used for deternination of antimicrobial susceptibility. Ten antimicrobials including penicillin, amoxicillin, trimethoprim-sulfometoxazole, erythromycin, meropenem, streptomycin, ofloxacin, ciprofloxacin, chloramphenicol, and clindamycin were tested. As a result of PCR, all isolates were confirmed as fully virulent field strains of B. anthracis. All isolates were found as susceptible to penicillin, amoxicillin, ofloxacin and ciprofloxacin. Since the last studies in the region, a change in the antimicrobial profile of B. anthracis strains was observed only for trimethoprim-sulfomethoxazole among the antimicrobials tested, a transition from susceptibility to resistance. In conclusion, penicillin and amoxicillin, are still the antibiotic of first choice for the prophylaxis and treatment of anthrax. Ofloxacin and ciprofloxacin are also effective enough to be prescribed for treatment. |
| Anahtar Kelimeler |
| Animal | Antimicrobial susceptibility | Bacillus anthracis | Human | PCR | Soil |
| Makale Türü | Özgün Makale |
| Makale Alt Türü | SSCI, AHCI, SCI, SCI-Exp dergilerinde yayımlanan tam makale |
| Dergi Adı | Kafkas Universitesi Veteriner Fakultesi Dergisi |
| Dergi ISSN | 1300-6045 |
| Dergi Tarandığı Indeksler | SCI-Expanded |
| Dergi Grubu | Q3 |
| Makale Dili | İngilizce |
| Basım Tarihi | 01-2025 |
| Cilt No | 31 |
| Sayı | 1 |
| Sayfalar | 125 / 132 |
| Doi Numarası | 10.9775/kvfd.2024.33033 |
| Makale Linki | https://doi.org/10.9775/kvfd.2024.33033 |
| Atıf Sayıları |
