Investigation of the Effect of Omega-3 Fatty Acids on Antioxidant System and Serum Aluminum, Zinc, and Iron Levels in Acute Aluminum Toxicity
Yazarlar (5)
Prof. Dr. Emine ATAKİŞİ
Kafkas Üniversitesi, Türkiye
Prof. Dr. Onur ATAKİŞİ
Kafkas Üniversitesi, Türkiye
Öğr. Gör. Melek ÖZTÜRKLER DÜNDAR
Kafkas Üniversitesi, Türkiye
Dr. Öğr. Üyesi Kezban YILDIZ DALGINLI
Kafkas Üniversitesi, Türkiye
Öğr. Gör. Çağatay ÖZBEY
Kafkas Üniversitesi, Türkiye
| Makale Türü | Özgün Makale (SSCI, AHCI, SCI, SCI-Exp dergilerinde yayınlanan tam makale) | ||
| Dergi Adı | Biological Trace Element Research (Q2) | ||
| Dergi ISSN | 0163-4984 Wos Dergi Scopus Dergi | ||
| Dergi Tarandığı Indeksler | SCI-Expanded | ||
| Makale Dili | İngilizce | Basım Tarihi | 06-2025 |
| Cilt / Sayı / Sayfa | 203 / 0 / 3208–3217 | DOI | 10.1007/s12011-024-04402-2 |
| Makale Linki | https://doi.org/10.1007/s12011-024-04402-2 | ||
| Özet |
| Aluminum (Al), one of the three most prevalent metals in the Earth’s crust, adversely impacts all metabolic systems of living organisms due to its extensive utilization by humans. It is known that omega-3 fatty acids (ω-3FA) protect the organism against diseases and have positive effects on the immune system. The aim of the study was to investigate the effect of ω-3FA on 8-OH-2-deoxyguanosine (8-OHdG), glutathione (GSH) levels and adenosine deaminase (ADA), paraoxonase (PON), and catalase (CAT) activities in rats with acute aluminum toxicity. The study also aimed to investigate the antioxidant system, as well as Al, zinc (Zn), and iron (Fe) levels. Forty Sprague–Dawley rats (n = 40) were used in the study and the rats were divided into four equal groups (n = 10). In group I, 0.5 mL of 0.9% saline solution (NaCI) was injected intraperitoneally. Group II was injected with 34 mg/kg aluminum chloride (AlCI3 … |
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