Does new onset and pre-existing atrial fibrillation predict mortality in COVID-19 patients?
Yazarlar (9)
Emrah Aksakal Sağlık Bilimleri Üniversitesi, Türkiye
Faruk Aydınyılmaz
Türkiye
İbrahim Saraç Atatürk Üniversitesi, Türkiye
Sidar Şiyar Aydın Atatürk Üniversitesi, Türkiye
Prof. Dr. Kamuran Kalkan Sağlık Bilimleri Üniversitesi, Türkiye
Makale Türü Açık Erişim Özgün Makale (ESCI dergilerinde yayınlanan tam makale)
Dergi Adı The Egyptian Heart Journal
Dergi ISSN 2090-911X Dergi Bilgileri (2022)
Dergi Tarandığı Indeksler ESCI
Makale Dili İngilizce Basım Tarihi 07-2022
Kabul Tarihi 24-06-2022 Yayınlanma Tarihi 07-07-2022
Cilt / Sayı / Sayfa 74 / 0 / – DOI 10.1186/s43044-022-00291-9
Makale Linki http://dx.doi.org/10.1186/s43044-022-00291-9
UAK Araştırma Alanları
Kardiyoloji
Özet
Coronavirus Disease-2019 (COVID-19), caused by Severe Acute Respiratory Syndrome-Coronavirus-2, still remains prevalent and severe. We aimed to evaluate the effects of pre-existing atrial fibrillation and new-onset atrial fibrillation (NOAF) on the clinical severity and mortality of COVID-19. Between April and December 2020, 5577 patients with positive PCR and/or COVID-19 compatible findings in computed tomography hospitalized were enrolled retrospectively. Total and in-hospital mortality, need for intensive care unit (ICU), need for mechanical ventilation, and recurrent hospitalization results of 286 patients with pre-existing AF before hospitalization and 82 patients with NOAF during hospitalization were evaluated. Preexisting AF was associated with a 2-fold increase in total and in-hospital mortality [OR (2.16 (1.62-2.89), 2.02 (1.48-2.76), P < 0.001, respectively]. NOAF was associated with a 14-fold increase in total mortality and a 12-fold increase in in-hospital mortality [OR(14.72 (9.22-23.5), 12.56 (8.02-19.68), P < 0.001], respectively]. However, pre-existing AF and NOAF resulted in increased ICU admission, mechanical ventilation, and recurrent hospitalization. In the Cox regression analysis, NOAF was observed as an independent risk factor for mortality. Pre-existing AF and in-hospital NOAF were associated with increased mortality and severity in hospitalized COVID-19 patients. In addition, NOAF was observed as an independent prognostic indicator in terms of total mortality.
Anahtar Kelimeler
Atrial fibrillation | COVID-19 | Mortality
Pdf İndir Creative Commons License
BM Sürdürülebilir Kalkınma Amaçları
Atıf Sayıları
Yöksis 9
PubMed 9
Does new onset and pre-existing atrial fibrillation predict mortality in COVID-19 patients?