| Yazarlar (1) |
Dr. Öğr. Üyesi Şükran YEDİEL ARAS
Kafkas Üniversitesi, Türkiye |
| Özet |
| The aim of this study was to investigate the effects of vitamin D and nettle (Urtica dioica L.) extract on SOD-2 and TNF-α levels in liver tissue of rats induced with TNBS (2,4,6 Trinitrobenzene Sulfonic Acid) by immunohistochemical methods. All rats used in the study were weighed and randomly divided into four groups. Liver tissue samples were taken at the end of the experiment. They were blocked in paraffin by applying routine tissue tracking procedure. Histologic and immunohistochemical methods were applied to the sections taken from the paraffin blocks. It was determined that histopathologic changes were intense in the TNBS group and less in the TNBSD and TNBSI groups. Strong SOD-2 immunoreactivity was detected in the cytoplasm of hepatocytes in control and TNBSD groups, weak in TNBS group and moderate in TNBSI group. TNF-α immunoreactivity was weak in the cytoplasm of hepatocytes in control group, strong in TNBS group, and moderate in TNBSD and TNBSI groups. In conclusion, it is thought that vitamin D and nettle extract may have positive effects on liver tissue and both substances may be protective against liver damage due to their antioxidant and anti-inflammatory effects. |
| Anahtar Kelimeler |
| Makale Türü | Özgün Makale |
| Makale Alt Türü | Diğer hakemli uluslarası dergilerde yayımlanan tam makale |
| Dergi Adı | Journal of Advances in VetBio Science and Techniques |
| Dergi ISSN | 2548-1150 |
| Dergi Tarandığı Indeksler | TRDizin, CAB International (CABI) index, Index Copernicus International (ICI) World of Journals, Google Scholar, Academic Research Index (Research Bib), Root Society for Indexing and Impact Factor Service (Rootindexing), Eurasian Scientific Journal Index (ESJI), Cosmos Impact Factor, Scientific Indexing Services (SIS), OpenAIRE, Directory of Open Access Scholarly Resources (ROAD), and CiteFactor databases. |
| Makale Dili | İngilizce |
| Basım Tarihi | 12-2024 |
| Cilt No | 9 |
| Sayı | 3 |
| Sayfalar | 197 / 205 |
| Doi Numarası | 10.31797/vetbio.1428195 |
| Makale Linki | https://doi.org/10.31797/vetbio.1428195 |
| Atıf Sayıları |
