Photoorganocatalytic synthesis, characterization, crystal structure of two schiff bases and their In Vitro and In Silico evaluations as cholinesterase inhibitors
Yazarlar (12)
Ajdar Medjidov
Institute Of Catalysis And Inorganic Chemistry Named After Academician M.Nagiyev Ministry Of Science, Azerbaycan
Institute Of Catalysis And Inorganic Chemistry Named After Academician M.Nagiyev Ministry Of Science, Azerbaycan
Rayyat İsmayilova
Institute Of Catalysis And Inorganic Chemistry Named After Academician M.Nagiyev Ministry Of Science, Azerbaycan
Institute Of Catalysis And Inorganic Chemistry Named After Academician M.Nagiyev Ministry Of Science, Azerbaycan
Dilgam Tagiyev
Institute Of Catalysis And Inorganic Chemistry Named After Academician M.Nagiyev Ministry Of Science, Azerbaycan
Institute Of Catalysis And Inorganic Chemistry Named After Academician M.Nagiyev Ministry Of Science, Azerbaycan
Doç. Dr. Mustafa SERTÇELİK Kafkas Üniversitesi, Türkiye
Tuncer Hökelek
Hacettepe Üniversitesi, Türkiye
Hacettepe Üniversitesi, Türkiye
Mansura Huseynova
Academician A.M. Guliyev Institute Of Chemistry Of Additives Ministry Of Science And Education Repub, Azerbaycan
Academician A.M. Guliyev Institute Of Chemistry Of Additives Ministry Of Science And Education Repub, Azerbaycan
Perizad Fatullayeva
Institute Of Catalysis And Inorganic Chemistry Named After Academician M.Nagiyev Ministry Of Science, Azerbaycan
Institute Of Catalysis And Inorganic Chemistry Named After Academician M.Nagiyev Ministry Of Science, Azerbaycan
Furkan Çakır Bezmiâlem Vakıf Üniversitesi, Türkiye
Halil Şenol Bezmiâlem Vakıf Üniversitesi, Türkiye
Nastaran Sadeghıan Bartin Üniversitesi, Türkiye
Aamer Saeed
Quaid-İ-Azam University, Pakistan
Quaid-İ-Azam University, Pakistan
Parham Taslımı Bartin Üniversitesi, Türkiye
| Makale Türü | Özgün Makale (SSCI, AHCI, SCI, SCI-Exp dergilerinde yayınlanan tam makale) | ||
| Dergi Adı | Journal of Molecular Structure (Q2) | ||
| Dergi ISSN | 0022-2860 Wos Dergi Scopus Dergi | ||
| Dergi Tarandığı Indeksler | SCI-Expanded | ||
| Makale Dili | Türkçe | Basım Tarihi | 05-2025 |
| Cilt / Sayı / Sayfa | 1329 / 1 / – | DOI | 10.1016/j.molstruc.2025.141396 |
| Makale Linki | https://doi.org/10.1016/j.molstruc.2025.141396 | ||
| Özet |
| Given that substances containing an imine or azomethine fragment are included in the group of physiologically active substances, the synthesis of new Schiff bases or the development of new synthesis methods for existing ones is of interest. Two Schiff bases were synthesized by the photoorganocatalytic method and characterized by elemental analysis, UV–Vis, IR spectroscopy and X-ray single-crystal analysis. The reactions were carried out under light irradiation (household lamps 2 × 15 W) with stirring at room temperature without heating, resulting in yields of 83 and 80 %, respectively for I and II. To obtain the target product, aromatic aldehydes 5-bromosalicylic aldehyde and ortho-vanillin, as well as 2-amino-5-methylpyridine, derivatives of pyridine, representatives of heterocyclic amines, were used. Compounds were prepared by the aldol condensation. Cognitive impairment, known as dementia is typically … |
| Anahtar Kelimeler |
| Aromatic aldehydes | Crystal structure | Enzyme inhibition | Hirshfeld surface analysis | In silico | Photoorganocatalytic synthesis |